Near complete visual recovery and refractive stability in modern corneal transplantation: Descemet membrane endothelial keratoplasty (DMEK)

Dijk, Korine van; Ham, Lisanne; Tse, Win Hou Willy; Liarakos, Vasilios S.; Quilendrino, Ruth; Yeh, Ru-Yin; Melles, Gerrit R.J.

doi:10.1016/j.clae.2012.10.066

Cited by 112 publications

(87 citation statements)

References 44 publications

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“…In our study, eyes in group B showed a higher rebubbling rate (30.4%) compared with eyes in group A (6.7%). The rebubbling rate in recent studies is reported to range between 3% and 62% after DMEK 8,9 and between 2.5% and 16.1%…”

Section: Discussionmentioning

confidence: 97%

“…5 More recently, Descemet membrane endothelial keratoplasty (DMEK) has been described as a sole transplantation of the Descemet membrane (DM) and corneal endothelium. 6 Despite visual outcome of unsurpassed quality, [7][8][9] only a few corneal surgeons have adopted this technique. One of the major reasons is that postoperative detachment of the thinner grafts occurs more frequently in DMEK 7,8 than detachment of thicker stromal grafts in DSAEK.…”

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confidence: 99%

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Graft Adhesion in Descemet Membrane Endothelial Keratoplasty Dependent on Size of Removal of Host’s Descemet Membrane

et al. 2014

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that reviewed the medical records of 200 consecutive patients undergoing DMEK. Fifty-three eyes of 51 patients undergoing DMEK for Fuchs endothelial dystrophy fulfilling the inclusion criteria were enrolled in this study. Based on intraoperative drawings, postoperative slitlamp examination, and photographs, eyes were divided into 2 groups. The diameter of the descemetorhexis was approximately 10 mm in group A (30 eyes), resulting in a peripheral 1-mm zone of denuded stroma between the graft and the host's Descemet membrane, and approximately 6 mm in group B (23 eyes), resulting in a peripheral 1-mm zone of overlapping between the graft and the host's Descemet membrane. MAIN OUTCOMES AND MEASURESGraft detachment rate, extent of graft detachment (in clock hours of graft's circumference), and rebubbling rate.RESULTS Four days after DMEK, the graft detachment rate was 33.3% (10 of 30) in group A and 78.3% (18 of 23) in group B (P = .002). The mean (SD) extent of graft detachment was 0.6 (0.9) and 2.8 (2.5) clock hours in groups A and B, respectively (P < .001), 4 days after surgery. The rebubbling rate was 6.7% (2 of 30) and 30.4% (7 of 23) for groups A and B, respectively (P = .03). CONCLUSIONS AND RELEVANCEA larger descemetorhexis in DMEK is correlated with better graft adhesion and lower rebubbling rates. Therefore, patients with a larger descemetorhexis require less intensive follow-up.

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Section: Discussionmentioning

confidence: 97%

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confidence: 99%

Graft Adhesion in Descemet Membrane Endothelial Keratoplasty Dependent on Size of Removal of Host’s Descemet Membrane

et al. 2014

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“…[7][8][9] In addition, phakic patients having endothelial keratoplasty are at increased risk for cataract progression, and we have 1 0886-3350 ARTICLE previously recommended strong consideration of a DMEK triple procedure for patients older than 50 years. 10 The achieved corrected distance visual acuity (CDVA) of DMEK (previously reported to be 20/20 or better in 41% to 46%, 20/25 or better in 80%, and 20/30 or better in 98% of patients 11,12 ) can allow a shift in the goal of the corneal transplant surgeon from simple rehabilitation to a targeted refractive result.…”

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confidence: 99%

Refractive outcomes of Descemet membrane endothelial keratoplasty triple procedures (combined with cataract surgery)

Schoenberg

Price

Miller

et al. 2015

Journal of Cataract and Refractive Surgery

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“…[1][2][3][4][5] It is replacing DSEK and becoming the preferred procedure for the treatment of endothelial dysfunction. 6,7 However, obstacles in performing DMEK remain.…”

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confidence: 99%

Clinical Outcomes of Descemet Membrane Endothelial Keratoplasty Using Eye Bank–Prepared Tissues

Deng

Sanchez

Chen

2015

American Journal of Ophthalmology

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Near complete visual recovery and refractive stability in modern corneal transplantation: Descemet membrane endothelial keratoplasty (DMEK)

Cited by 112 publications

References 44 publications

Graft Adhesion in Descemet Membrane Endothelial Keratoplasty Dependent on Size of Removal of Host’s Descemet Membrane

Graft Adhesion in Descemet Membrane Endothelial Keratoplasty Dependent on Size of Removal of Host’s Descemet Membrane

Refractive outcomes of Descemet membrane endothelial keratoplasty triple procedures (combined with cataract surgery)

Clinical Outcomes of Descemet Membrane Endothelial Keratoplasty Using Eye Bank–Prepared Tissues

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