Near-Field Detection of Aβ Proteins Using Micro Beads

Abstract

In this paper, we present the possibility of quantification analysis for A captured by micro beads using Near-filed detection. In order to evaluate detection efficiency, detected signals were compared with different sizes of micro beads and a varied number of micro beads. Also, A deposits and A binding to micro beads were measured, therefore, we observed the A deposit and light scattering around the surface of micro beads induced by attached A . This method can be used for quantitative analysis for not only the number of A , but also the binding ratio of A to micro beads.