Near Field Optics and Scanning Near Field Optical Microscopy

Fischer, Ulrich; Koglin, Jason E.; Naber, A.; Raschewski, A.; Tiemann, R.; Fuchs, Harald

doi:10.1007/978-94-009-1657-9_9

Cited by 3 publications

(2 citation statements)

References 38 publications

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“…Ideally, one would like to combine the high resolution of these techniques with the sensitivity, specificity, and flexibility afforded by optical techniques. This goal has driven the development of near-field scanning optical microscopy (NSOM or SNOM) which can be used to conduct optical measurements with a spatial resolution beyond the classical diffraction limit. − …”

Section: Introductionmentioning

confidence: 99%

Near-Field Scanning Optical Microscopy

1999

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working in the area of ultrafast spectroscopy. From there he spent two years as a postdoctoral fellow at Pacific Northwest Laboratory before joining the faculty at the University of Kansas in 1995. His research interests include the study of artificial membranes, protein channels, and single molecule dynamics using novel high-resolution techniques. His group is also active in developing nanometric chemical sensors and in exploring new techniques for highresolution optical measurements.

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Section: Introductionmentioning

confidence: 99%

Near-Field Scanning Optical Microscopy

1999

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“…The near-field scanning optical microscope (NSOM) (Pohl et al, 1984;Lewis et al, 1984) provides lateral resolutions superior to all other optical (far field) microscopes, i.e. in the range of a few nanometres (Betzig et al, 1993;Zenhausern et al, 1995;Fischer et al, 1996). The classical Rayleigh diffraction limit of approximately half the wavelength (l/2) is surpassed by scanning a small tip (typically a micropipette (Harootunian et al, 1986) or an optical fibre (Betzig et al, 1991) drawn down to a diameter <100 nm) in the proximity of the sample surface.…”

Section: Introductionmentioning

confidence: 99%

Shear force imaging of DNA in a near‐field scanning optical microscope (NSOM)

Kirsch

Meyer

Jovin

1997

Journal of Microscopy

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SummaryA near-field scanning optical module has been constructed as an accessory for a Nanoscope IIIa commercial scanning probe microscope. Distance feedback and topographic registration are accomplished with an uncoated optical fibre scanning tip by implementation of the shear force technique. The tip is driven by a piezoelectric actuator at a resonance frequency of 8-80 kHz. A laser diode beam is scattered by the tip and detected by a split photodiode, with lock-in detection of the difference signal. The amplitude (r) and phase (v) responses were characterized as a function of the calibrated tip-sample separation. Using an r cos v feedback signal, imaging of pUC18 relaxed circular plasmid DNA spread on mica precoated with cetylpyridinium chloride was achieved. The apparent width (28 Ϯ 5 nm) was approximately four times that achieved by scanning force measurements with the same instrument; the apparent height of the DNA (0 : 6 Ϯ 0 : 3 nm) was similar with the two techniques. These results demonstrate the applicability of the shear force signal for imaging biological macromolecules according to topography and in conjunction with the optical signals of a near-field scanning optical microscope (NSOM).

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Scanning Near-Field Optical Microscopy

Fischer¹

1998

Scanning Probe Microscopy

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Near Field Optics and Scanning Near Field Optical Microscopy

Cited by 3 publications

References 38 publications

Near-Field Scanning Optical Microscopy

Near-Field Scanning Optical Microscopy

Shear force imaging of DNA in a near‐field scanning optical microscope (NSOM)

Scanning Near-Field Optical Microscopy

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