2021
DOI: 10.1177/17085381211032826
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Near-infrared fluorescence imaging with indocyanine green for quantification of changes in tissue perfusion following revascularization

Abstract: Objectives Current diagnostic modalities for patients with peripheral artery disease (PAD) mainly focus on the macrovascular level. For assessment of tissue perfusion, near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) seems promising. In this prospective cohort study, ICG NIR fluorescence imaging was performed pre- and post-revascularization to assess changes in foot perfusion. Methods ICG NIR fluorescence imaging was performed in 36 patients with PAD pre- and post-intervention. After intr… Show more

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Cited by 8 publications
(6 citation statements)
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“…In a study of 36 patients imaged with ICG-FI before and after a PAD intervention, time–intensity curves were plotted for three regions of interest—over the dorsum of the foot, the forefoot, and the hallux with the unaffected contralateral as a control. 15 There was a significant increase for the maximum slope and AUC egress in all three ROIs, with the maximum slope seen in the hallux (3.7%/s to 6.6%/s, p < 0.001). 15 Future studies are needed to predict favorable outcome of revascularization procedures.…”
Section: Endpoint Measuresmentioning
confidence: 77%
See 4 more Smart Citations
“…In a study of 36 patients imaged with ICG-FI before and after a PAD intervention, time–intensity curves were plotted for three regions of interest—over the dorsum of the foot, the forefoot, and the hallux with the unaffected contralateral as a control. 15 There was a significant increase for the maximum slope and AUC egress in all three ROIs, with the maximum slope seen in the hallux (3.7%/s to 6.6%/s, p < 0.001). 15 Future studies are needed to predict favorable outcome of revascularization procedures.…”
Section: Endpoint Measuresmentioning
confidence: 77%
“…In a study of 36 patients imaged with ICG-FI before and after a PAD intervention, time-intensity curves were plotted for three regions of interest-over the dorsum of the foot, the forefoot, and the hallux with the unaffected contralateral as a control. 15 There Fig. 2 Faster mean transit time after recanalization at the region of interest.…”
Section: Indocyanine Green Fluorescence Imagingmentioning
confidence: 99%
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