Near-infrared spectroscopy: A methodology-focused review

Pellicer, Adelina; Bravo, María Carmen

doi:10.1016/j.siny.2010.05.003

Cited by 212 publications

(190 citation statements)

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“…Changes in blood volume to the tissue are then estimated by taking the sum of the calculated haemoglobin concentrations (i.e. total haemoglobin) [5].…”

Section: Introductionmentioning

confidence: 99%

Investigation of photoplethysmography, laser doppler flowmetry and near infrared spectroscopy during induced thermal stress

Budidha

Abay

Kyriacou

2015

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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“…Changes in blood volume to the tissue are then estimated by taking the sum of the calculated haemoglobin concentrations (i.e. total haemoglobin) [5].…”

Section: Introductionmentioning

confidence: 99%

Investigation of photoplethysmography, laser doppler flowmetry and near infrared spectroscopy during induced thermal stress

Budidha

Abay

Kyriacou

2015

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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“…Using NIRS, regional HbO 2 , HHb, total Hb (HbT = HbO 2 + HHb), and difference Hb (HbD = HbO 2 − HHb) in the underlying cerebral tissue can be measured. Spatially resolved techniques or the multidistance approach allows for calculating the ratio of HbO 2 to HbT, expressed by the various manufacturers as the tissue oxygenation index (TOI, %) [50] or the regional oxygen saturation (rSO 2 , %), respectively [51]. Assuming a relative constant cerebral metabolism and therefore oxygen consumption as well as a stable venous and capillary blood volume, it is thought that trends in rSO 2 or TOI reflect trends in regional CBF [52].…”

Section: Techniquementioning

confidence: 99%

Measuring cerebrovascular autoregulation in preterm infants using near-infrared spectroscopy: an overview of the literature

Kooi¹,

Verhagen

Elting

et al. 2017

Expert Review of Neurotherapeutics

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(2017) Measuring cerebrovascular autoregulation in preterm infants using near-infrared spectroscopy: an overview of the literature, Expert Review of Neurotherapeutics, 17:8, 801-818, DOI: 10.1080/14737175.2017 Introduction:The preterm born infant's ability to regulate its cerebral blood flow (CBF) is crucial in preventing secondary ischemic and hemorrhagic damage in the developing brain. The relationship between arterial blood pressure (ABP) and CBF estimates, such as regional cerebral oxygenation as measured by near-infrared spectroscopy (NIRS), is an attractive option for continuous non-invasive assessment of cerebrovascular autoregulation. Areas covered: The authors performed a literature search to provide an overview of the current literature on various current clinical practices and methods to measure cerebrovascular autoregulation in the preterm infant by NIRS. The authors focused on various aspects: Characteristics of patient cohorts, surrogate measures for cerebral perfusion pressure, NIRS devices and their accompanying parameters, definitions for impaired cerebrovascular autoregulation, methods of measurements and clinical implications. Expert commentary: Autoregulation research in preterm infants has reported many methods for measuring autoregulation using different mathematical models, signal processing and data requirements. At present, it remains unclear which NIRS signals and algorithms should be used that result in the most accurate and clinically relevant assessment of cerebrovascular autoregulation. Future studies should focus on optimizing strategies for cerebrovascular autoregulation assessment in preterm infants in order to develop autoregulation-based cerebral perfusion treatment strategies. ARTICLE HISTORY

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“…The primary chromophores of interest are oxyhemoglobin (HbO 2 ), deoxyhemoglobin (Hb) and cytochrome c oxidase, because the concentration of these chromophores varies with time and oxygenation status (Elwell & Phil, 1995). Each chromophore has a unique absorption spectrum, where the specific extinction coefficient 1 (ε) is expressed as a function of the wavelength (Horecker, 1942;Pellicer & Bravo, 2011). ε describes how strongly a chromophore absorbs light at a particular wavelength.…”

Section: Absorption Of Lightmentioning

confidence: 99%

“…The typical application of the Beer-Lambert law is that A is experimentally measured (at n wavelengths for n chromophores of interest), Assuming that d is the inter-optode distance and ε 1 … ε n has been found previously for each chromophore, the objective is to find C 1 …C n (Pellicer & Bravo, 2011). Accurate estimation of chromophore concentration requires (at a minimum) the same number of wavelengths, as there are chromophores in the given tissue.…”

Section: Attenuation By Lightmentioning

confidence: 99%