Near Infrared Spectroscopy for Noninvasive Assessment of Claudication

Kooijman, H.M.; Hopman, Maria T. E.; Colier, Willy N.J.M.; Vliet, J.A. van der; Oeseburg, B.

doi:10.1006/jsre.1997.5164

Cited by 95 publications

(103 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our value of 0.016 mL per 100 g/min is in the low range of these values. For blood flow, we also found a wide range of values in the literature: 0.28 -0.57 (42), 2.3 (47), 0.70 (45), 1.45 (10), and 0.65 mL per 100 g/min (12). In a PET study (46), those values ranged from 2.2 to 9.3 mL per 100 g/min.…”

Section: Mapssupporting

confidence: 67%

See 1 more Smart Citation

Regional Differences of Hemodynamics and Oxygenation in the Human Calf Muscle Detected with Near-Infrared Spectrophotometry

Wolf¹,

Wolf²,

Choi³

et al. 2007

Journal of Vascular and Interventional Radiology

View full text Add to dashboard Cite

PURPOSE: Measurements in muscle tissue are often performed at a selected single location over the muscle of interest. The hypothesis is that the values obtained reflect the status within the entire muscle or muscle group. This, however, may not be the case. The study was performed to investigate whether this hypothesis is true for hemodynamics and oxygenation in the healthy human calf muscle at rest. MATERIALS AND METHODS:Hemoglobin flow, blood flow, oxygen consumption, and venous hemoglobin oxygen saturation were mapped at 22 locations in 30 legs of 15 healthy subjects (nine women, six men aged 26 -37 years) simultaneously by using frequency-domain near-infrared spectrophotometry with a specially designed probe during venous occlusion. RESULTS: For all parameters, spatial heterogeneity was found between subjects and within individual legs. All parameters were highly significantly different when comparing proximal and distal regions. Differences were also found between medial and lateral regions. The global mean values (؎standard deviation) over all measurements were as follows: hemoglobin flow, 1.27 mol per 100 mL/min ؎ 0.88; blood flow, 0.56 mL per 100 g/min ؎ 0.38; oxygen consumption, 0.016 mL per 100 g/min ؎ 0.011; and venous oxygen saturation, 77.6% ؎ 5.9. The thickness of the overlying adipose tissue had an influence on the measurements and must be considered. CONCLUSION: Highly significant spatial heterogeneity of hemodynamics and oxygenation was found in the healthy human calf muscle. J Vasc Interv Radiol 2007; 18:1094 -1101Abbreviations: ATT ϭ adipose tissue thickness, DPF ϭ differential pathlength factor, NIRS ϭ near-infrared spectrophotometry, SvO 2 ϭ venous oxygen saturation, TRV ϭ test-retest variability, VO 2 ϭ oxygen consumption NEAR-INFRARED spectrophotometry (NIRS) is a valuable tool for measuring hemodynamics and oxygenation in human tissue. NIRS is noninvasive, provides real-time measurements, is costeffective, is feasible at the bedside, and is easily repeatable and reproducible and, therefore, suitable for use in the clinical setting. Because NIRS provides measurements at the level of arterioles, capillaries, and venules (1) several centimeters deep in the tissue, it is a complementary method to Doppler, which probes larger blood vessels, laser Doppler flowmetry, which measures superficial blood vessels, and imaging techniques such as magnetic resonance (MR) imaging, positron emission tomography (PET), and radiography, which depend on the use of ionizing radiation and/or contrast media. NIRS has been applied to infants and adults to measure hemodynamics and oxygenation in many fields such as the brain, but one particularly promising field is the skeletal muscle (2-5). Studies in the skeletal muscle have included measurements in sports medicine (6,7) and in patients with peripheral vascular disease (8 -17), myopathies (18 -20), and heart failure (21-23).Measurements in muscle tissue are often performed at a selected single location over the muscle of interest. The values obtained are consider...

show abstract

Section: Mapssupporting

confidence: 67%

“…This also implies that our data are internally consistent. In the literature, we found a wide range of values for VO 2 in the human calf muscle: 0.026 -0.14 (42), 0.050 -0.097 (44), 0.01 (45), 0.13 (10), and 0.047 mL per 100 g/min (12). In a PET study (46), those values ranged from 0.08 to 0.66 mL per 100 g/min.…”

Section: Mapsmentioning

confidence: 94%

Regional Differences of Hemodynamics and Oxygenation in the Human Calf Muscle Detected with Near-Infrared Spectrophotometry

Wolf¹,

Wolf²,

Choi³

et al. 2007

Journal of Vascular and Interventional Radiology

View full text Add to dashboard Cite

show abstract

“…PAD is emphasized in muscle research because it is associated with a rather high morbidity and has a distinctly detrimental effect on the patient's health and quality of life. 5,[18][19][20] Since diseases such as PAD induce tissue-level effects related to the skeletal muscle hemodynamics, it is most efficient to study these diseases by the examination of local muscle hemodynamics. Invasive methods of monitoring local muscle hemodynamics all suffer the same weakness in that they are clinically more dangerous due to increasing the risk of infection, inducing some degree of stress in the patient, and being inapplicable for continuous monitoring during dynamic protocols.…”

Section: Introductionmentioning

confidence: 99%

Hybrid diffuse optical techniques for continuous hemodynamic measurement in gastrocnemius during plantar flexion exercise

et al. 2015

View full text Add to dashboard Cite

Abstract. Occlusion calibrations and gating techniques have been recently applied by our laboratory for continuous and absolute diffuse optical measurements of forearm muscle hemodynamics during handgrip exercises. The translation of these techniques from the forearm to the lower limb is the goal of this study as various diseases preferentially affect muscles in the lower extremity. This study adapted a hybrid near-infrared spectroscopy and diffuse correlation spectroscopy system with a gating algorithm to continuously quantify hemodynamic responses of medial gastrocnemius during plantar flexion exercises in 10 healthy subjects. The outcomes from optical measurement include oxy-, deoxy-, and total hemoglobin concentrations, blood oxygen saturation, and relative changes in blood flow (rBF) and oxygen consumption rate (r _ VO 2 ). We calibrated rBF and r _ VO 2 profiles with absolute baseline values of BF and _ VO 2 obtained by venous and arterial occlusions, respectively. Results from this investigation were comparable to values from similar studies. Additionally, significant correlation was observed between resting local muscle BF measured by the optical technique and whole limb BF measured concurrently by a strain gauge venous plethysmography. The extensive hemodynamic and metabolic profiles during exercise will allow for future comparison studies to investigate the diagnostic value of hybrid technologies in muscles affected by disease.

show abstract

“…Importantly, it has been reported that RT reflects the severity of intermittent claudication in arteriosclerosis obliterans. 11 Therefore we expect that evaluation of Hb will prove useful for predicting claudication of the gluteal muscles after aortic surgery, because aortic clamping can be considered equivalent to a surrogate load test for the gluteal muscles, such as walking exercise, 11 as well as an occlusion test for evaluation of intermittent caludication in arteriosclerosis obliterans. However, further investigations of these complications will be necessary.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, near-infrared spectroscopy (NIRS) 1 has been used to evaluate muscle deoxygenation 2,3 and various vascular diseases, [4][5][6][7] including intermittent claudication accompanying arteriosclerosis obliterans. [8][9][10][11] In this study we examined how NIRS of the buttocks might reflect changes in the arterial flow of the pelvic area during aortic surgery, and tried to evaluate the circulatory changes caused by abdominal aortic clamping and reperfusion of individual distal arteries.…”

mentioning

confidence: 99%

Use of Near-Infrared Spectroscopic Measurement at the Buttocks During Abdominal Aortic Surgery.

Fukui

Urayama

Tanaka

et al. 2002

Circ J

View full text Add to dashboard Cite

uring abdominal aortic surgery, dynamic changes occur in the circulation of the pelvic area, but until now there was no method of evaluating them. Recently, near-infrared spectroscopy (NIRS) 1 has been used to evaluate muscle deoxygenation 2,3 and various vascular diseases, 4-7 including intermittent claudication accompanying arteriosclerosis obliterans. [8][9][10][11] In this study we examined how NIRS of the buttocks might reflect changes in the arterial flow of the pelvic area during aortic surgery, and tried to evaluate the circulatory changes caused by abdominal aortic clamping and reperfusion of individual distal arteries. MethodsWe studied 22 patients who underwent aneurysmectomy and prosthetic graft replacement for abdominal aortic aneurysm (AAA). The patients comprised 21 men and 1 woman, aged 73±6 years. Twenty-one of the patients underwent bifurcated graft replacement, and 1 underwent a straight graft replacement. The patients who received bifurcated grafts were divided into groups A and B. Group A comprised 17 patients who underwent reconstruction of the bilateral common iliac artery and ligation of the inferior mesenteric artery (IMA) in the usual manner. Patients who first underwent reconstruction of the left common iliac artery were classified as group A•I (6 cases) and those who first underwent reconstruction of the right common iliac artery were classified as group A•II (11 cases). Group B comprised 4 patients who underwent other patterns of arterial reconstruction for extended iliac aneurysms. The NIRS probe was mounted on the center of the left buttock (approximately 5 cm cranial to the center of the large gluteal muscle) during the AAA repair operation. Measurements were taken using a NIRS oxygen electrode monitor (OMRON HEO-200). Changes in oxy-and deoxy-hemoglobin (Hb) concentration after clamping of the abdominal aorta were measured. We focused mainly on changes in oxy-Hb. Oxy-and deoxy-Hb concentrations changed proportionately in all cases. The recovery time (RT) was defined as the interval from aortic declamping (or declamping of the main artery feeding the left buttock) to the point where the oxy-and deoxy-Hb curves crossed over. The mean changes in Hb values and RTs were expressed as the mean ± SD. ResultsDistinct types of circulatory changes in the gluteal muscles were detected by NIRS. In all cases the Hb values reflected decreased arterial flow because of aortic clamping During abdominal aortic surgery, dynamic changes occur in the pelvic circulation. Near-infrared spectroscopy (NIRS) was used in this study to evaluate arterial flow in the buttocks as a monitor of arterial flow in the pelvic area during abdominal aortic surgery. Twenty-two patients who underwent abdominal aortic aneurysmectomy comprised the study group. The NIRS probe was mounted on the left buttock during surgery, and the changes in oxy-and deoxy-hemoglobin (

show abstract

Near Infrared Spectroscopy for Noninvasive Assessment of Claudication

Cited by 95 publications

References 25 publications

Regional Differences of Hemodynamics and Oxygenation in the Human Calf Muscle Detected with Near-Infrared Spectrophotometry

Regional Differences of Hemodynamics and Oxygenation in the Human Calf Muscle Detected with Near-Infrared Spectrophotometry

Hybrid diffuse optical techniques for continuous hemodynamic measurement in gastrocnemius during plantar flexion exercise

Use of Near-Infrared Spectroscopic Measurement at the Buttocks During Abdominal Aortic Surgery.

Contact Info

Product

Resources

About