2013
DOI: 10.1016/j.diagmicrobio.2013.04.029
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Near point-of-care administration by the attending physician of the rapid influenza antigen detection immunochromatography test and the fully automated respiratory virus nucleic acid test: contribution to patient management

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Cited by 18 publications
(12 citation statements)
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“…However, these tests are time consuming and costly, so they are rarely used clinically in Japan 24. Before introduction of RIADTs to Japan in 1999, physicians diagnosed influenza by assessing clinical symptoms and epidemiological information.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…However, these tests are time consuming and costly, so they are rarely used clinically in Japan 24. Before introduction of RIADTs to Japan in 1999, physicians diagnosed influenza by assessing clinical symptoms and epidemiological information.…”
Section: Discussionmentioning
confidence: 99%
“…Following the addition of 200 µL of UTM containing materials expressed from the nasopharyngeal swabs, the analysis began; this consisted of a programmed, totally automated extraction, reverse transcriptase-PCR (RT-PCR) and hybridisation sequence. The final readout of the microarray was made by the insertion of the slide array into a reader 24. The result for each virus type, ‘Detected’ or ‘Not detected,’ was displayed on a monitor.…”
Section: Methodsmentioning
confidence: 99%
“…While enzyme immunoassay based point-of-care tests (POCTs) for influenza and RSV have been available for several years, a health technology appraisal found little benefit of using these devices in a near-patient setting (Nicholson et al, 2014). Moreover, these tests have lower sensitivities compared to PCR-based devices (Boku et al, 2013;DiMaio et al, 2012;Goldenberg and Edgeworth, 2015). A new multiplex PCR-based POCT, Enigma® MiniLab™ FluAB-RSV PCR assay (Enigma Diagnostics Ltd, Salisbury, UK), became available in 2015.…”
Section: Introductionmentioning
confidence: 99%
“…Clinical evaluations have reported sensitivities of 96.6% to 100% for influenza virus A, 96.8% to 100% for influenza virus B, and 89.8% to 91.7% for RSV, with specificities of Ͼ96.5% for all targets (100,103,104), which in one comparative study was superior to results for a traditional RT-PCR test (103).…”
Section: Multiplex Nucleic Acid Testsmentioning
confidence: 95%