Neck circumference and other clinical features in the diagnosis of the obstructive sleep apnoea syndrome.

Davies, Robert J. O.; Ali, Noorjahan; Stradling, John

doi:10.1136/thx.47.2.101

Cited by 415 publications

(288 citation statements)

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“…significantly correlated with more severe SA (Rosenow et al 1996). The PPNC has been shown to be highly predictive of the apnoea/hypopnea-index in patients with acromegaly Therapy unrelated obstructive SA (Davies et al 1992). These data Whenever possible acromegaly is treated by resection of the suggest that upper airway obstruction plays a major role in pituitary adenoma.…”

Section: Introductionmentioning

confidence: 72%

“…These drugs or external SA (Horner et al 1989), but rather due to hypertrophy of radiation are also used when operative treatment is not possible. para-and retropharyngeal tissues and tongue as suggested All these treatments can lead to normalization of GH (Nabarro earlier (Cadieux et al 1982;Guilleminault and van den Hoed 1987), and for most of them case reports of subsequent 1979; Hart et al 1985;Mezon et al 1980;Rosenow et al 1996). improvement of sleep exist (Chanson et al 1986; Rosenstock Several pieces of evidence support the obstructive nature Ziemer and Dunlap 1988).…”

Section: Introductionmentioning

confidence: 97%

“…Hypertension commonly shows nocturnal accentuation and In active acromegaly, Pekkarinen et al (1987) reported SA responds to nCPAP-therapy in up to 40% of patients in 5 of 11 consecutive patients and Hart et al (1985) diagnosed . Conversley, 35% of acromegalic SA in 4 (19%) of 21 patients.…”

Section: Introductionmentioning

confidence: 99%

“…Pre-and especially acromegaly patients with one year postoperative GH-levels postoperatively, the use of sedative medication should be of < 3 ng/mL. Conversely, after studying 11 and 21 patients, minimized and constant monitoring of oxhemoglobin respectively, Perks et al (1980) and Hart et al (1985) claimed saturation and vital functions is mandatory. that SA was more common or only present in active acromegaly.…”

Section: Introductionmentioning

confidence: 99%

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Sleep apnoea in endocrine diseases

Rosenow

McCarthy

Caruso

1998

Journal of Sleep Research

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The pertinent literature on the prevalence, clinical manifestations and pathogenic mechanisms of sleep apnoea (SA) in endocrine diseases, namely acromegaly, Cushing syndrome, hypothyroidism and diabetes mellitus was reviewed. An increased prevalence is well documented in patients with active and treated acromegaly. While most authors report peripheral obstruction, due to hypertrophy of tongue and pharyngeal tissues, to be the cause of SA in acromegaly, some findings argue for a role of hormone‐induced changes of central respiratory control. SA is also more common in hypothyroidism, especially when myxedema is present. The associated edema and myopathy appear to be of pathogenic importance. Thyroxin substitution is frequently effective for the treatment of SA but nCPAP can be necessary initially and in some patients even after remission of clinical signs of hypothyroidism. In Cushing disease and syndrome, parapharyngeal fat accumulation can cause SA, but no epidemiological information is available. In non insulin dependent diabetes (NIDDM), obesity is the common risk factor for both, nocturnal hypoxia and insulin resistance. In IDDM, the development of autonomic neuropathy may predispose to SA. Where treatment of the underlying endocrine disease is unable cure the associated SA, nCPAP is usually the treatment of first choice. More prospective studies are clearly needed to establish prevalences and resolve the controversies regarding pathogenesis.

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Section: Introductionmentioning

confidence: 72%

Section: Introductionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Sleep apnoea in endocrine diseases

Rosenow

McCarthy

Caruso

1998

Journal of Sleep Research

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“…There are various other studies showing strong correlation between OSAS, neck circumference and BMI 10,15,16,17 . In our study they were not statistically significant.…”

Section: Discussionmentioning

confidence: 94%

Obstructive sleep apnoea syndrome-Clinical diagnosis versus limited channel diagnostic nocturnal polysomnography

Renjit¹,

Job²,

Michael³

2014

Int Jour of Biomed Res

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Diagnosis and Management of Obstructive Sleep Apnea

Gottlieb

Punjabi

2020

JAMA

854

580

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ImportanceObstructive sleep apnea (OSA) affects 17% of women and 34% of men in the US and has a similar prevalence in other countries. This review provides an update on the diagnosis and treatment of OSA.ObservationsThe most common presenting symptom of OSA is excessive sleepiness, although this symptom is reported by as few as 15% to 50% of people with OSA in the general population. OSA is associated with a 2- to 3-fold increased risk of cardiovascular and metabolic disease. In many patients, OSA can be diagnosed with home sleep apnea testing, which has a sensitivity of approximately 80%. Effective treatments include weight loss and exercise, positive airway pressure, oral appliances that hold the jaw forward during sleep, and surgical modification of the pharyngeal soft tissues or facial skeleton to enlarge the upper airway. Hypoglossal nerve stimulation is effective in select patients with a body mass index less than 32. There are currently no effective pharmacological therapies. Treatment with positive airway pressure lowers blood pressure, especially in patients with resistant hypertension; however, randomized clinical trials of OSA treatment have not demonstrated significant benefit on rates of cardiovascular or cerebrovascular events.Conclusions and RelevanceOSA is common and the prevalence is increasing with the increased prevalence of obesity. Daytime sleepiness is among the most common symptoms, but many patients with OSA are asymptomatic. Patients with OSA who are asymptomatic, or whose symptoms are minimally bothersome and pose no apparent risk to driving safety, can be treated with behavioral measures, such as weight loss and exercise. Interventions such as positive airway pressure are recommended for those with excessive sleepiness and resistant hypertension. Managing asymptomatic OSA to reduce cardiovascular and cerebrovascular events is not currently supported by high-quality evidence.

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Neck circumference and other clinical features in the diagnosis of the obstructive sleep apnoea syndrome.

Abstract: Background Neck circumference has

Cited by 415 publications

References 18 publications

Sleep apnoea in endocrine diseases

Sleep apnoea in endocrine diseases

Obstructive sleep apnoea syndrome-Clinical diagnosis versus limited channel diagnostic nocturnal polysomnography

Diagnosis and Management of Obstructive Sleep Apnea

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