Neck circumference as an independent indicator to non-alcoholic fatty liver disease in non-obese men

Abstract

Background To investigate the relationship of the neck circumference (NC) with non-alcoholic fatty liver disease (NAFLD) in non-obese Chinese population.MethodsOur data were obtained from a cross-sectional survey on the prevalence of metabolic diseases and risk factors in East China in 2014. Subjects with a BMI ≥ 18.5 kg/m2 and < 25 kg/m2 were considered normal weight. A total of 2668 participants aged 18–89 were identified for analysis. Anthropometric indices, biochemical parameters, clinical characteristics and abdominal ultrasound were measured. Independent predictors of NAFLD were identified by multiple logistic regressions.ResultsThe overall prevalence of NAFLD was 10.94 % in this study population and men had a higher prevalence than women (19.89 % vs 7.48 %, P < 0.01). The mean NC was greater in NAFLD subjects compared with other groups in both genders (P < 0.01). NC was correlated to BMI, waist circumference, hip circumference, systolic blood pressure, diastolic blood pressure, insulin, HOMA-IR, triglycerides and ALT, regardless of sex. In the highest quartile of NC levels in men but not in women, the risks were substantially higher for NAFLD [odds ratio 2.18, (95 % confidence interval 1.16–4.13)] (P < 0.001 for trend) after adjusting for potential confounding factors.ConclusionNC was an independent indicator for NAFLD in normal weighted men.

Association between neck circumference and non-alcoholic fatty liver disease in Mexican children and adolescents with obesity

“…We found clinical significance in Tanner stages 2-3 and Tanner stages 4-5 in our male population, but NC was not significant by NAFLD at ROC curves in our female population. These results match the findings of the study by Li et al, in which they only found clinically significant associations in their eutrophic adult male population [18].…”

“…There are limited studies regarding the association between NC and NAFLD, and most of them deal only with adult populations. However, the few studies performed in child population with obesity have shown positive correlations, with differences between male and female genders [17][18][19].…”

Associations of blood lead levels with reproductive hormone levels in men and postmenopausal women: Results from the SPECT-China Study

“…The registration number is ChiCTR-ECS-14005052 (www.chictr.org.cn). Details about the study have been published previously111213. Briefly, from February to June 2014, 16 residential areas in Shanghai, Jiangxi Province and Zhejiang province were selected using a stratified and clustered method.…”

Association Between Neck Circumference and Blood Pressure: A Systematic Review and Meta-Analysis of Observational Studies

“…All studies were used cross-sectional data and had medium to high-quality. These studies were published between the year 2003 and 2017 and performed in the United states [21,25,48,51,55], China [19,20,23,28,29,53,56,57], India [27], Israel [38,39], Turkey [31,34,52], Korea [42], Japan [44], Iran [54], Spain [26], Bulgaria [50], Portugal [43], Brazil [30,40,47] and Saudi Arabia [49]. The results of most studies revealed that there is positive correlation between NC and blood pressure.…”

“…It is suggested that NC can be used to predict and diagnose of HTN [22]. Also, NC has been recently at the center of attention in all age groups including children, adolescent and adults [20,23,24].…”