Necrobiose lipoídica em adolescente com diabetes mellitus tipo 1: relato de caso

Abstract

Este artigo está licenciado sob forma de uma licença Creative Commons Atribuição 4.0 Internacional, que permite uso irrestrito, distribuição e reprodução em qualquer meio, desde que a publicação original seja corretamente citada. ABSTRACTAIMS: To report a case of necrobiosis lipoidica, a rare chronic granulomatous dermatosis. CASE DESCRIPTION: We present the case of a 17-year-old male adolescent, with type 1 diabetes mellitus from the age of four, followed in the Pediatric-Diabetology clinics of a level II hospital, under intensive regimen with multiple insulin administrations and poor metabolic control. At the age of 15, he noticed the appearance of an asymptomatic, erythematous, infiltrated, oval-shaped plaque, with a waxy whitish center, well-defined borders, 5 cm in diameter and progressive growth, located on the left forearm. The histological examination confirmed the diagnosis of necrobiosis lipoidica. He was treated with topical corticosteroid and emollient, thus stabilizing and reducing lesion infiltration. CONCLUSIONS: The authors highlight a rare dermatosis, non-pathognomonic of diabetes mellitus but related to this diagnosis in most cases. Its challenging recognition, especially in the presence of recent onset lesions, with atypical clinical presentation or in unusual sites, is fundamental in order to avoid erroneous or late treatments and its progression to ulceration.

Necrobiosis lipoidica in childhood: a review of literature with emphasis on therapy

“…There were 27 case reports and two case series that included 31 cases in total (Table 1). 6,11–38 No prospective or retrospective studies were included as none were detected in the search of literature. All available details, such as the exact length of treatment or dosage of medication, are listed in Table 1; most patients received multiple therapies.…”

Literaturrecherche zur Therapie der Necrobiosis lipoidica in der Kindheit

“…Es gab 27 Fallberichte und zwei Fallserien, die insgesamt 31 Fälle umfassten (Tabelle 1). 6,11–38 Alle verfügbaren Details, wie die genaue Dauer der Behandlung oder die Dosierung der Medikamente, sind in Tabelle 1 aufgeführt; die meisten Patienten erhielten mehrere Therapien.…”