Necrobiosis Lipoidica Diabeticorum

Hildebrand, Alice G.

doi:10.1001/archinte.1940.00190160068007

Cited by 57 publications

(4 citation statements)

References 15 publications

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“…Forty‐two per cent of their non‐diabetic patients developed impaired glucose tolerance/DM, contrasting with just 7% of our patient group. Some of the discrepancies may be explained by the fact that cortisone glucose tolerance tests were performed: these have given conflicting results in other studies 9 –12 . However, the techniques used in these studies were not comparable.…”

Section: Discussionmentioning

confidence: 94%

Necrobiosis lipoidica: only a minority of patients have diabetes mellitus

O’Toole

Kennedy

Nolan

et al. 1999

British Journal of Dermatology

147

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Although it is commonly accepted that necrobiosis lipoidica (NL) is associated with diabetes mellitus (DM), there is some controversy regarding the degree of this association. In a retrospective review of 65 patients with NL attending our dermatology out-patient clinics we found that just seven (11%) were known to have DM at the time of presentation. Seven further patients (11%) were diagnosed as having impaired glucose tolerance/DM at presentation and over a 15-year follow-up period. Thus, only a minority of our patients with NL had DM.

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Section: Discussionmentioning

confidence: 94%

Necrobiosis lipoidica: only a minority of patients have diabetes mellitus

O’Toole

Kennedy

Nolan

et al. 1999

British Journal of Dermatology

147

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“…The vascular changes in NLD are well known (15). In cases ofNLD and DM, these vascular changes have been attributed to the diabetic microangiopathy (14,(16)(17)(18). The relationship between GA and DM is controversial.…”

Section: Discussionmentioning

confidence: 99%

Psoriasis, Necrobiosis Lipoidica, Granuloma Annulare, Vitiligo and Skin Infections in the Same Diabetic Patient

Abraham

Lahat

Kinarty

et al. 1990

The Journal of Dermatology

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“…He demonstrated by means of the polarizing microscope a few doubly refracting crystals in the centers of the lipid foci and with appropriate staining "a marked degree of fatty infiltration, elastic dystrophy and a surrounding foam-cell and histiocytic infiltration." Klaber stated that each new lesion in his patient was preceded by irritation and observed that each passed at varying rates through several phases: (1) Initially, a small fawn-coloured infiltrated papule.…”

Section: Commentmentioning

confidence: 99%