Necrolytic migratory ulceration

Pakran, Jaheersha; Riyaz, Najeeba

doi:10.4103/2229-5178.115518

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…Causes of NME include glucagon-induced cutaneous necrolysis, hypoaminoacidemia-induced epidermal protein deficiency and necrolysis, dietary or metabolic zinc or essential fatty acids deficiency, glucagon-induced inflammatory mediators, and a wide range of malabsorption ( 93 ). Pakran et al ( 36 ) reported a 53-year-old female patient with NME. Her skin lesions responded to oral zinc sulfate and monthly octreotide injections.…”

Section: Endocrine and Metabolic Diseasesmentioning

confidence: 99%

Trace element zinc and skin disorders

Pan

Yang

et al. 2023

Front. Med.

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Zinc is a necessary trace element and an important constituent of proteins and other biological molecules. It has many biological functions, including antioxidant, skin and mucous membrane integrity maintenance, and the promotion of various enzymatic and transcriptional responses. The skin contains the third most zinc in the organism. Zinc deficiency can lead to a range of skin diseases. Except for acrodermatitis enteropathic, a rare genetic zinc deficiency, it has also been reported in other diseases. In recent years, zinc supplementation has been widely used for various skin conditions, including infectious diseases (viral warts, genital herpes, cutaneous leishmaniasis, leprosy), inflammatory diseases (hidradenitis suppurativa, acne vulgaris, rosacea, eczematous dermatitis, seborrheic dermatitis, psoriasis, Behcet's disease, oral lichen planus), pigmentary diseases (vitiligo, melasma), tumor-associated diseases (basal cell carcinoma), endocrine and metabolic diseases (necrolytic migratory erythema, necrolytic acral erythema), hair diseases (alopecia), and so on. We reviewed the literature on zinc application in dermatology to provide references for better use.

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Section: Endocrine and Metabolic Diseasesmentioning

confidence: 99%

Trace element zinc and skin disorders

Pan

Yang

et al. 2023

Front. Med.

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Hand Dermatitis: an Allergist’s Nightmare

Wold

Chen

Lampel

2014

Curr Allergy Asthma Rep

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Hand dermatitis is a common skin complaint. We use our hands to explore our environment; subsequently, our hands are in frequent contact with potential allergens and irritants. Patients with hand dermatitis may present to their allergist with this complaint. Approaching the diagnosis and treatment of hand dermatitis can be challenging, as both internal and external factors may contribute to the overall condition. Furthermore, the differential diagnosis of hand dermatitis is broad and the cause often multifactorial. Obtaining a thorough history and performing a focused examination may help the clinician differentiate between multiple causes of hand dermatitis. Numerous treatment options exist for hand dermatitis, and new potential treatments are in development as well. We aim to provide the allergist with a streamlined toolkit for help in the diagnosis and management of hand dermatitis.

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Necrolytic migratory ulceration

Cited by 2 publications

References 7 publications

Trace element zinc and skin disorders

Trace element zinc and skin disorders

Hand Dermatitis: an Allergist’s Nightmare

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