Necrotizing fasciitis as a late complication of multimodal treatment for locally advanced head and neck cancer: A case report

Abstract

Severe infectious complications of chemoradiation for locally advanced head and neck cancer may occur months after completion of treatment. The recognition of these late side effects is crucial so as to accurately ascertain the long-term morbidity and benefits of organ-preservation protocols in this setting.

Cervico‐facial necrotizing fasciitis

“…Medical therapy such as steroids or chemotherapy for cancer can also cause immune compromise and be associated with NF. In one case report, NF leading to septic shock occurred 9 months following completion of chemoradiation therapy for head and neck cancer (Maluf et al , 2007).…”

Cervical necrotizing fasciitis and myositis in a western lowland gorilla (Gorilla gorilla gorilla)

“…Specific causes of cervical fasciitis in humans commonly include dental disease, oropharyngeal disease, complications of cancer treatment, and otitis media [4, 5, 10, 12, 14, 15]. The gorilla of this case report had a fistulous tract in the oropharyngeal cavity, which was the likely origin of the fasciitis.…”

Necrotizing fasciitis as a complication of taxanes: a case report

“…In our patient, there was no other predisposing factor found for the development of necrotizing fasciitis apart from the fact that the patient was on docetaxel at the time of infection, where she received 3 cycles 12 days prior to admission. It has been documented that chemotherapy leading to alterations on the mucosa, softtissue, and skin along with immunosuppression might be a triggering factor [7] . The skin toxicity (including dry skin, erythema, pigmentation, pruritus, rash/desquamation, urticaria, dermatitis, and other) has been reported in previous studies [8] .…”