Necrotizing fasciitis caused by group A streptococcus

Mikić, Dragan; Bojić, I; Djokic, Milomir; Stanic, Vojkan; Stepić, V.; Micevic, Dusko; Rudnjanin, Slobodan; Radosavljević, Aleksandar; Micic, Jovanka; Tomanovic, Branka; Begovic, Vesna; Popović, Svetlana

doi:10.2298/vsp0202203m

Cited by 6 publications

(4 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There was a significant correlation between STSS and prognosis. In patients with STSS, mortality is about 80%–100%, while in those without STSS, mortality is about 30% 21 . The time of diagnosis of NF is also important to prognosis.…”

Section: Discussionmentioning

confidence: 99%

“…In patients with STSS, mortality is about 80%-100%, while in those without STSS, mortality is about 30%. 21 The time of diagnosis of NF is also important to prognosis. Multivariate logistic regression analysis showed that surgical debridement time delay of more than 24 h from admission was the only independent risk factor for prognosis after adjusting for age, sex, diabetes, and hypotension on admission.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A case of streptococcus necrotizing fasciitis secondary to acute tonsillitis and review of literatures

Liu

Huang

et al. 2018

Hong Kong Journal of Emergency Medicine

View full text Add to dashboard Cite

Necrotizing fasciitis, officially named by Wilson in 1952, was a rare potentially life-threatening necrotizing soft tissue infections disease. The main lesions showed subcutaneous fat and fascia layer in progressive necrosis, generally not involving muscles. It was characterized by acute onset, rapid progress, and dangerous condition, often accompanied by systemic toxin shock, which was a relatively rare clinical acute critical disease with high mortality rate. Necrotizing fasciitis is a rare but clinical critical disease. The overall incidence of necrotizing fasciitis is approximately 0.04 cases per 1000 persons in the United States, the 30-day mortality is 27%, and necrotizing fasciitis–related mortality in Asian region is about 28%. Streptococcus pyogenes (group A streptococcus) are human-specific pathogens that can cause upper respiratory tract infection such as tonsillitis, associated with post-infection diseases such as rheumatic fever, and also can induce severe invasive diseases such as necrotizing fasciitis and streptococcus toxin shock syndrome. This article reports a case of streptococcus necrotizing fasciitis secondary to suppurative tonsillitis, which was seldom reported before and our successful management with delayed debridement. This study was anonymous and was approved by the local Research Ethics Committee. Informed consent was obtained from the patient.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A case of streptococcus necrotizing fasciitis secondary to acute tonsillitis and review of literatures

Liu

Huang

et al. 2018

Hong Kong Journal of Emergency Medicine

View full text Add to dashboard Cite

show abstract

“…GAS infection-related in-hospital case fatality rate is reported to be about 11% [ 1 ]. The incidence of the GAS infection has been reported to increase during the last 10–20 years due to the increasing colonization of the GAS in general population [ 2 ]. Hemolytic streptococcus gangrene is a fatal disease that causes systemic illness and multisystem failures, such as bacteremia, renal impairment, hepatitis, acute thrombocytopenia and respiratory failure.…”

Section: Introductionmentioning

confidence: 99%

A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis

et al. 2018

View full text Add to dashboard Cite

BackgroundHemolytic streptococcus gangrene is a life threatening invasive bacterial infection. Hemolytic streptococcus gangrene in the danger triangle of the face is too lethal to operate. A case of the confirmed hemolytic streptococcus gangrene in the danger triangle of the face caused by Group A beta-hemolytic streptococcus (GAS) in 20-months old boy is presented to draw attention of clinicians to this uncommon but frequently fatal infection.Case presentationPreviously healthy 20 months old boy suddenly developed paranasal gangrene on the left side of the danger triangle of the face, followed by rapidly progressive thrombocytopenia and hepatitis. The clinical features, liver function, and hematological and serological parameters resembled to a description of streptococcal toxic shock syndrome (STSS). Aggressive antibiotics, substitutional and supportive therapy were conducted without surgical debridement of facial tissues. Prompt diagnosis and aggressive timely treatment completely cured the disease in 28 days.ConclusionsThe present case report demonstrates prompt diagnosis and timely treatment as a strategy to cure the fatal hemolytic streptococcus gangrene located in too risky body part to operate.

show abstract

“…Hyperbaric oxygen as an adjunct treatment 3,15,18 . has been discussed upon but it has been decided not to be used because of clinical and radiological signs of good response on 9 previous therapeutic modalities and in order to accelerate closure of stump wound by administering negative pressure therapy.…”

mentioning

confidence: 99%

Above knee amputation due to necrotizing fasciitis caused by gas producing strain of Echerichia coli and negative pressure therapy assisted closure of large open wound

Pesic¹,

Tulencic-Egic²,

Zwick³

2023

VOJNOSANIT PREGL

View full text Add to dashboard Cite

Introduction. Nonclostridial gas-forming soft tissue infections (NGSTI) are rare, rapid progressive infections that are caracterized by high mortality and high proportion of amputations. Surgical debridement is crucial in therapy and it results in complex wounds that need to be closed to prevent secondary morbidity. Case report. Herein we present a case of NGSTI in a 68-year-old patient with diabetes mellitus with acute thrombosis of popliteal artery aneurysm and radiological signs of gas in his right leg and in urine bladder wall. Infection was caused by gas-forming strain of Escherichia coli. The patient was early treated with femoral amputation and antibiotics. A vacuum asistet closure (VAC) treatment has been applied. Administered VAC therapy resulted in primary wound closure without complications 17 days after surgery. Conclusion. Negative pressure increase wound fluid removal and infection clerance while, also, increases wound contraction and aproximation of skin flaps. VAC therapy can be good adjunctive treatment for closure of large open wounds for the patients with NGSTI to avoid extensive reconstructive surgery.

show abstract

Necrotizing fasciitis caused by group A streptococcus

Cited by 6 publications

References 19 publications

A case of streptococcus necrotizing fasciitis secondary to acute tonsillitis and review of literatures

A case of streptococcus necrotizing fasciitis secondary to acute tonsillitis and review of literatures

A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis

Above knee amputation due to necrotizing fasciitis caused by gas producing strain of Echerichia coli and negative pressure therapy assisted closure of large open wound

Contact Info

Product

Resources

About