Necrotizing fasciitis in neonate by Lichtheimia ramosa : A case study

Abstract

Zygomycetes have been known to cause life-threatening infections in humans which are often difficult to treat. We present a rare case of cutaneous mucormycosis in a premature neonate admitted with neonatal sepsis and necrotizing fasciitis. He was diagnosed with Lichtheimia ramosa infection and managed surgically along with Amphotericin B. Low birth weight, prematurity, respiratory distress, administration of corticosteroid and broad spectrum antibiotics were identified as the potential risk factors in this case which had led to the fungal infection. Early diagnosis and prompt management is critical in prevention of morbidity and mortality associated with the disease.

Discovery of a New Lichtheimia (Lichtheimiaceae, Mucorales) from Invertebrate Niche and Its Phylogenetic Status and Physiological Characteristics

“…Habitat: Isolated from soil [ 7 ], cow dung [ 7 ], guinea-pig lung [ 7 ], Musa sapientum [ 7 ], hay [ 7 ], culture contaminant [ 7 ], composting soils [ 22 ], meju [ 42 ], Homo sapiens (wound, lung, skin, sputum, gastric juice, pneumonia, bronchoalveolar lavage) [ 7 , 46 , 47 , 48 , 49 , 50 ], Moutai-flavor Daqu [ 51 ], fresh press-mud [ 52 ], green coffee bean [ 53 ], nuruk [ 54 ], Bos taurus [ 55 ], bovine liver tissue [ 56 ], soil [ 57 ], bandages [ 58 ], ovine milk [ 59 ], marine sediments [ 60 ], clinical sample [ 61 ], and Theuronema hilgendorfi hilgendorfi (this study).…”

“…Distribution: Indonesia [ 7 ], Netherlands [ 7 ], Switzerland [ 7 ], Ghana [ 7 ], India [ 7 , 46 , 49 , 60 ], Germany [ 7 , 50 ], Greece [ 7 ], Spain [ 7 , 59 ], Belgium [ 7 ], Japan [ 55 ], China [ 47 , 48 , 51 ], Mexico [ 22 , 57 ], France [ 58 ], Brazil [ 52 , 53 ], Egypt [ 61 ], Korea [ 42 , 54 , 56 ] and this study.…”

Delayed diagnosis and management of necrotizing fasciitis of the left lower leg: A case report

“…NF can occur at any age, but it is particularly common in elderly men and very rare in children. [5,8] It tends to affect the limbs, trunk, perineum, and other body parts [9–12] (Table 1). The risk factors of NF include old age, smoking, alcohol use, obesity, diabetes, peripheral vascular disease, liver disease, tumors, and prolonged high-dose steroid use, of which diabetes is the most common risk factor.…”

“…NF can occur at any age, but it is particularly common in elderly men and very rare in children. [5,8] It tends to affect the limbs, trunk, perineum, and other body parts [9][10][11][12] (Table 1).…”

Comment on ‘Necrotizing fasciitis in neonate by Lichtheimia ramosa: A case study’

“…We read with interest the article by William et al ., which reported necrotizing fasciitis in neonate by Lichtheimia ramosa [ 1 ]. However, we would like to offer some constructive points to enrich this report.…”