Necroulcerative hemorrhagic gastritis in a cat secondary to the administration of 3% hydrogen peroxide as an emetic agent

Obr, Teresa D.; Fry, Joanna K.; Lee, Justine A.; Hottinger, Heidi

doi:10.1111/vec.12639

Cited by 9 publications

(11 citation statements)

References 17 publications

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“…Veterinarians should be aware of the possibility of hemorrhagic necroulcerative gastritis after administration of this agent. 13 Endoscopy is an effective tool for the removal of objects from the gastrointestinal tract of cats and showed high success and low complication rates in the present study as a first-line treatment modality. 2 The cats in our paper were mostly older, and many had pre-existing medical conditions; therefore, avoiding a longer duration of anesthesia and surgical procedures may be beneficial.…”

Section: Discussionmentioning

confidence: 54%

Foreign body ingestion due to detachment of pill dispenser tips in cats: a retrospective study of 13 cases

M de Souza,

Alves,

Castro

et al. 2023

Journal of Feline Medicine and Surgery

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Objectives The aim of this study was to evaluate and describe 13 cases in which a pet piller broke during the administration of medication, and the tip was accidentally ingested by the cat. Methods A total of 15 presentations to the clinic were identified in a private practice database involving 13 cats in which the silicone tip broke. Two of these cats ingested foreign bodies on two separate occasions. Routine radiographic examination enabled the identification of silicone tips in all animals. On 2/15 occasions, the cats did not receive an emetic drug. Intramuscular xylazine (0.2 mg/kg) and dexmedetomidine (6 μg/kg) were administered to 12/15 and 1/15 cats, respectively. Results The cats were aged 3–17 years (mean age 11.00 ± 4.35 years). Vomiting occurred in 13 cats that received alpha-2 adrenoceptor agonists, although the silicone tip was recovered in only five occurrences. In 9/15 occurrences, endoscopy was performed under general inhalation anesthesia, and the silicone tip was successfully removed. Natural elimination occurred in only one case. Conclusions and relevance The use of pet pillers with detachable silicone tips increases the risk of accidental foreign body ingestion by animals. Therefore, guidelines regarding safety standards for manufacturing would be beneficial. No cat in this series developed clinical signs related to the ingestion of the piller tip, probably because of the quick presentation by the owners and early intervention, including endoscopic retrieval. Surgical intervention was not required in any case, including one in which the foreign body was lodged within the small intestine before being passed naturally by the cat.

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Section: Discussionmentioning

confidence: 54%

Foreign body ingestion due to detachment of pill dispenser tips in cats: a retrospective study of 13 cases

M de Souza,

Alves,

Castro

et al. 2023

Journal of Feline Medicine and Surgery

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“…The use of 3% H 2 O 2 administration as an emetic is not recommended in cats, and there are no reports describing acute respiratory distress after its administration [2–4]. Oral administration of 3% H 2 O 2 solution in cats can result in necroulcerative gastritis as a sequela [3].…”

Section: Discussionmentioning

confidence: 99%

“…Irritation and inflammation of the mucous membrane in the pharynx, esophagus, and stomach, resulting from H 2 O 2 ingestion and pain should be considered as a possible cause of inappetence. Some articles have reported the risk of hemorrhagic and necroulcerative hemorrhagic gastritis following 3% H 2 O 2 administration as an emetic in cats; therefore, it is not recommended in this species [3, 6].…”

Section: Discussionmentioning

confidence: 99%

“…H 2 O 2 is used as a common agent to induce emesis in dogs during first aid, but its use in cats is not recommended [2–4]. Solutions with an H 2 O 2 concentration higher than 3% should not be orally administered because of the potential adverse effects, such as laryngospasm, foam formation in the mouth with a risk of aspiration, severe mucosal damage, repeated vomiting, hematemesis, necroulcerative gastritis (especially in cats), oxygen embolism, and systemic intoxication [3–7]. H 2 O 2 inhalation may cause cough and transient dyspnea because of severe irritation and inflammation of the mucous membranes.…”

Section: Introductionmentioning

confidence: 99%

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Acute Respiratory Failure after Administration of Hydrogen Peroxide as an Emetic in a Cat

Raušerová-Lexmaulová

Agudelo

Prokesova

2019

Case Reports in Veterinary Medicine

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Objective and Case Summary This case report describes a 5-year-old domestic short-haired cat that was orally administered with 4 mL of 3% hydrogen peroxide by the owner after suspecting ingestion of a foreign body by the cat. Shortly after the administration, the cat developed severe respiratory distress. Thoracic radiography showed an interstitial-to-alveolar pulmonary pattern, while echocardiography and heart injury markers ruled out a cardiac origin. Intensive management with oxygen, diuretics, bronchodilators, and sedation resulted in survival of the cat without further respiratory complications. New and Unique Information Provided To the best of our knowledge, this is the first report of a lung injury and acute respiratory failure after administration of hydrogen peroxide in a cat with successful management.

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“…Other agents previously recommended to induce emesis that are no longer recommended include salt/salt water (as it can cause life‐threatening hypernatraemia), mustard, syrup of ipecac and hydrogen peroxide. Although hydrogen peroxide was shown to have minimal adverse effects in one retrospective study (Kahn and others 2012), a prospective experimental study found significant overt and histopathological gastric lesions in dogs after administration of 3 per cent hydrogen peroxide (Niedswecki and others 2017) and severe necroulcerative haemorrhagic gastritis has been described in a cat after its use (Obr and others 2017).…”

Section: Decontaminationmentioning

confidence: 99%

Intoxication in dogs and cats: a basic approach to decontamination

Humm¹,

Greensmith²

2019

In Practice

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Background: There are two types of intoxicated patient that present to veterinary practices: the asymptomatic patient with a known exposure and the patient with clinical signs that may (or may not) be due to a toxin or poison. Deciding when (or if) to treat these patients is often an inexact science and the decision must be made based on numerous risk factors, the owner’s level of comfort with risk and any financial constraints.Aim of the article: This article is the first in a series of four and aims to provide a basic overview of the approach to decontamination of an asymptomatic patient presented with a known intoxication. It also outlines therapies that may be considered in both symptomatic and asymptomatic patients, and these will be discussed in more detail in future articles.

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Necroulcerative hemorrhagic gastritis in a cat secondary to the administration of 3% hydrogen peroxide as an emetic agent

Cited by 9 publications

References 17 publications

Foreign body ingestion due to detachment of pill dispenser tips in cats: a retrospective study of 13 cases

Foreign body ingestion due to detachment of pill dispenser tips in cats: a retrospective study of 13 cases

Acute Respiratory Failure after Administration of Hydrogen Peroxide as an Emetic in a Cat

Intoxication in dogs and cats: a basic approach to decontamination

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