Needle Biopsy in the Diagnosis of Testicular Leukemia in Children

Gill, Bhagwant; Kogan, Stanley J.; Rossman, Barry; Santorineou, Maria; Radel, Eva; Reda, Edward F.; Levitt, Selwyn B.

doi:10.1016/s0022-5347(17)41203-1

Cited by 9 publications

(1 citation statement)

References 9 publications

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“…Fine needle and core needle biopsies are both accurate for diagnosis. Needle biopsy specimens provide results that are similar to open wedge biopsies (18)(19)(20)(21). Microscopically the involved testicle shows focal or diffuse infiltration of leukemic blasts with effacement of the normal architecture (22), frequently arranged in a concentric fashion around tubules or vessels in the interstitial tissue (7).…”

Section: Resultsmentioning

confidence: 62%

Testicular involvement in pediatric acute lymphocytic leukemia: what to do about it?

et al. 2022

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Section: Resultsmentioning

confidence: 62%

Testicular involvement in pediatric acute lymphocytic leukemia: what to do about it?

et al. 2022

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Fine‐needle aspiration biopsy (FNAB) diagnosis of testicular involvement in acute lymphoblastic leukemia in children

Akhtar

Ali

Burgess

et al. 1991

Diagnostic Cytopathology

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A series of 106 fine-needle aspiration biopsy specimens obtained from the testes of children with acute lymphoblastic leukemia was reviewed retrospectively. Involvement by leukemia was seen in 34, there was no evidence of disease in 52, and the cellular sample was inadequate in 20. All aspiration smears, except those with leukemic involvement, showed a variable number of Sertoli cells. Testicular leukemia was diagnosed by the presence of numerous leukemic cells and rare or no Sertoli cells. Fine-needle aspiration biopsy is a simple but effective technique for diagnosing leukemic involvement of the testis in children with acute lymphoblastic leukemia.

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Fine‐needle aspiration cytology as a tool for the early detection of testicular relapse of acute lymphoblastic leukemia in children

Almeida¹,

Chagas²,

Sousa³

et al. 1994

Diagnostic Cytopathology

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Fine-needle aspiration cytology (FNAC) of the testis was done in 31 children (33 aspirates) with acute lymphoblastic leukemia (ALL) either as part of an end-therapy protocol (Group I, n = 20) or because of clinical suspicion of testicular relapse (Group II, n = 13). In Group I, none of the smears showed evidence of leukemic cells. However, two of these patients developed subsequent testicular relapse within 1 yr and were considered false-negative cases. Blast cells were present in nine patients of Group II; in the remaining four patients no neoplastic cells were observed in the smears and none experienced a relapse after a mean follow-up of 18 mo. Our findings indicate that FNAC can be a valuable method to evaluate clinically suspected testicular infiltration in children with ALL, and can be considered as an alternative procedure to surgical biopsy for screening testicular recurrence of childhood ALL.

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Needle Biopsy in the Diagnosis of Testicular Leukemia in Children

Cited by 9 publications

References 9 publications

Testicular involvement in pediatric acute lymphocytic leukemia: what to do about it?

Testicular involvement in pediatric acute lymphocytic leukemia: what to do about it?

Fine‐needle aspiration biopsy (FNAB) diagnosis of testicular involvement in acute lymphoblastic leukemia in children

Fine‐needle aspiration cytology as a tool for the early detection of testicular relapse of acute lymphoblastic leukemia in children

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