Needle in a Haystack: A Missed Case of Wound Botulism

Hudler, A.; Cataldo, Matthew; Major, Ajay; Lobo, Ingrid

doi:10.1016/j.amjmed.2019.03.014

Cited by 1 publication

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References 7 publications

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“…Wound botulism occurs when wounds become contaminated with C. botulinum spores, followed by the germination of these spores, toxin production, subsequently leading to paralysis. Wound botulism is a rare occurrence, often associated with intravenous abuse of black tar heroin (Trayner and McAuley, 2018;Hudler et al, 2019;Peak et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

The dilemma of diagnosing wound botulism in an infant: A rare case of paralysis with topical application of honey

Tamrin

2020

International Journal of Infectious Diseases

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Botulism is a form of paralysis caused by a neurotoxin produced by the bacterium Clostridium botulinum. It is well known that natural honey contains Clostridium botulinum spores; controversy arises when a honey-related product is being used for wound care, where the possibility occurs of applying these spores to an open wound. To our knowledge, no reported cases of medical-grade honey have been associated with wound botulism. Given this fact, do we feel secure regarding the safety of this product, and will it be enough to alleviate our concern? We present a case of an infant with an infected umbilical stump, which required a surgical wound debridement. This infant developed a sudden progressive flaccid paralysis a few days after the application of topical medical grade honey for wound care. Even though suspicion of wound botulism is high, confirmation of the diagnosis, detection of neurotoxin, and isolating the organism remains a challenge.

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Section: Introductionmentioning

confidence: 99%

The dilemma of diagnosing wound botulism in an infant: A rare case of paralysis with topical application of honey

Tamrin

2020

International Journal of Infectious Diseases

View full text Add to dashboard Cite

show abstract

Needle in a Haystack: A Missed Case of Wound Botulism

Cited by 1 publication

References 7 publications

The dilemma of diagnosing wound botulism in an infant: A rare case of paralysis with topical application of honey

The dilemma of diagnosing wound botulism in an infant: A rare case of paralysis with topical application of honey

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