Needling Versus Liquid Nitrogen Cryotherapy for the Treatment of Pedal Warts

Cunningham, D. J.; Brimage, Jessica T; Naraghi, Reza; Bower, Virginia M

doi:10.7547/0003-0538-104.4.394

Cited by 10 publications

(12 citation statements)

References 10 publications

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“…Our results for clearance conflict with the findings of the only other RCT of the needling procedure by Cunningham et al . This was a smaller study of 37 participants and showed a statistically significant difference in clearance rates favouring the needling group after 12 weeks, relative to cryotherapy.…”

Section: Discussioncontrasting

confidence: 99%

“…Our study followed the same treatment protocols as Longhurst and Cunningham, with the exception that participants in our needling group were given one treatment. Longhurst and Bristow reported a high resolution rate (38 of 45) after one needling treatment.…”

Section: Discussionmentioning

confidence: 99%

“…Longhurst and Bristow reported a high resolution rate (38 of 45) after one needling treatment. Cunningham et al . reported a median of 2 treatments, 5 weeks apart, and a mean of 1·61 ± 0·05 treatments, 5·08 ± 2·08 weeks apart.…”

Section: Discussionmentioning

confidence: 99%

“…To our knowledge, there is only one published randomized controlled trial (RCT) evaluating the effectiveness of the needling procedure . This trial randomized 37 participants to receive either needling or cryotherapy.…”

mentioning

confidence: 99%

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The EV erT2 (Effective Verruca Treatments 2) trial: a randomized controlled trial of needling vs. nonsurgical debridement for the treatment of plantar verrucae

et al. 2017

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SummaryBackground Verrucae are a common foot skin pathology, which can in some cases persist for many years. Plantar verrucae can be unsightly and painful. There are a range of treatment options including needling. Objectives The EVerT2 (Effective Verruca Treatments 2) trial aimed to evaluate the clinical and cost-effectiveness of the needling procedure for the treatment of plantar verrucae, relative to callus debridement. Methods This single-centre randomized controlled trial recruited 60 participants (aged ≥ 18 years with a plantar verruca). Participants were randomized 1 : 1 to the intervention group (needling) or the control group (debridement of the overlying callus). The primary outcome was clearance of the index verruca at 12 weeks after randomization. Secondary outcomes included recurrence of the verruca, clearance of all verrucae, number of verrucae, size of the index verruca, pain and participant satisfaction at 12 and 24 weeks. A cost-effectiveness analysis was carried out from the National Health Service perspective over 12 weeks. Results Sixty eligible patients were randomized (needling group n = 29, 48%; debridement group n = 31, 52%) and 53 were included in the primary analysis (needling n = 28, 97%; debridement n = 25, 81%). Clearance of the index verruca occurred in eight (15%) participants (needling n = 4, 14%; debridement n = 4, 16%; P = 0Á86). The needling intervention costs were on average £14Á33 (95% confidence interval 5Á32-23Á35) more per patient than for debridement. Conclusions There is no evidence that the needling technique is more clinically or cost-effective than callus debridement. The results show a significant improvement in pain outcomes after needling compared with the debridement treatment alone.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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The EV erT2 (Effective Verruca Treatments 2) trial: a randomized controlled trial of needling vs. nonsurgical debridement for the treatment of plantar verrucae

et al. 2017

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“…On the face of it this latest trial may not appear to be much of step forward; indeed it is not, but there are some lessons to be learned: The bright hope of needling as an effective treatment for plantar warts appears to have been somewhat dashed by this new trial. Two previous studies, a case series and a randomized trial, showed apparently promising results from this type of treatment with clearance rates of 60–70%. Altogether then, the needling story is beginning to look a bit like the duct tape story where a wave of enthusiasm followed the quirky Focht et al .…”

mentioning

confidence: 87%