As a result of Chinese economic growth in the 21st century, Chinese for Specific Purposes (CPS) has become a new paradigm for the teaching and learning of language. Despite some differences, it is reasonable to adapt the English for Specific Purposes (ESP) framework, in which a Needs analysis is fundamental for course design, into the CPS process. This study has two aims: to survey the need for nurses in Phuket to learn the Chinese language, and to suggest a course design for the target learners. Data were collected from 100 nurses working in three public hospitals on Phuket Island. The research instrument was an online questionnaire. The data were analyzed using descriptive statistics. The results show a high demand for learning Chinese, especially listening and speaking skills for communicating with patients and their relatives. Writing and reading skills are not highly desired by the target learners. Therefore, it is recommended that hospitals in Phuket should arrange in-house Chinese language courses, with course design based on the learners’ needs and preferences reported in this study.