Negative influence of antimicrobial therapy on radiolabeled white blood cells scintigraphy performance in infective endocarditis: myth or fact?

Kagna, Olga; Keidar, Zohar; Ben-Haim, S.

doi:10.1007/s12350-022-03119-w

Cited by 1 publication

(1 citation statement)

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“…Whether prior antibiotic treatment affects the diagnostic accuracy of nuclear imaging methods remains an area of debate. In a recent retrospective study on 153 patients who underwent 171 FDG PET/CT studies, including 119 studies performed while patients were receiving antibiotic therapy, no significant impact on the diagnostic performance of FDG PET/CT studies was found [101,102]. Another study on 80 patients did not reveal any influence of prolonged antibiotic therapy before the procedure on the imaging results [85].…”

Section: -Fluorodeoxyglucose Positron Emission Tomography/computed To...mentioning

confidence: 96%

Multimodality Imaging Diagnosis in Infective Endocarditis

Babes,

Bustea,

Ilias

et al. 2023

Life

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Imaging is an important tool in the diagnosis and management of infective endocarditis (IE). Echocardiography is an essential examination, especially in native valve endocarditis (NVE), but its diagnostic accuracy is reduced in prosthetic valve endocarditis (PVE). The diagnostic ability is superior for transoesophageal echocardiography (TEE), but a negative test cannot exclude PVE. Both transthoracic echocardiography (TTE) and TEE can provide normal or inconclusive findings in up to 30% of cases, especially in patients with prosthetic devices. New advanced non-invasive imaging tests are increasingly used in the diagnosis of IE. Nuclear medicine imaging techniques have demonstrated their superiority over TEE for the diagnosis of PVE and cardiac implantable electronic device infective endocarditis (CIED-IE). Cardiac computed tomography angiography imaging is useful in PVE cases with inconclusive TTE and TEE investigations and for the evaluation of paravalvular complications. In the present review, imaging tools are described with their values and limitations for improving diagnosis in NVE, PVE and CIED-IE. Current knowledge about multimodality imaging approaches in IE and imaging methods to assess the local and distant complications of IE is also reviewed. Furthermore, a potential diagnostic work-up for different clinical scenarios is described. However, further studies are essential for refining diagnostic and management approaches in infective endocarditis, addressing limitations and optimizing advanced imaging techniques across different clinical scenarios.

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Section: -Fluorodeoxyglucose Positron Emission Tomography/computed To...mentioning

confidence: 96%