Background
With the success of free autologous breast reconstruction, the abdominal donor site is now an important consideration, especially in patients of child-bearing age. In our institution, there are increasing patients who have successfully undergone the DIEP flap despite previous pregnancy. This study aims to answer questions on the effect of the donor site on pregnancy and vice versa.
Methods
A retrospective cohort study was conducted to identify breast cancer patients who received a free deep inferior epigastric artery perforator (DIEP) flap for breast reconstruction from 2018 January to 2020 August. Patients were allocated to two groups according to whether they had prior pregnancies with successful deliveries. Demographics, flap related parameters, surgical outcomes on breast and abdomen, and patient-reported outcome (Breast-Q questionaries) were analyzed. Patients were excluded if follow-up time was less than one year, or if there was incomplete medical records or Breast-Q replies.
Results
Ninety-nine of 116 patients had had successful pregnancies with delivery, 17 of them remained nulliparous. No statistically significant differences existed between groups regarding demographic data, flap related parameters, surgical outcomes on breast and abdomen. Nulliparous patients exhibited significantly lower score in physical well-being in the abdomen domain compared with delivery-experienced patients (62.1 versus 73.4, p = 0.025). Significantly, nulliparous patients felt more tightness and pulling of the abdominal wall than the delivery-experienced patients (2.9 versus 3.7; p = 0.05 and 3.5 versus 4.0; p = 0.04)
Conclusion
Free DIEP flap can be transferred safely in nulliparous patients despite a slight increase in abdominal tightness and abdominal pulling. Precise flap design and surgical approaches may help to minimize the abdominal discomfort especially on young, normal BMI and non-childbearing patients.