Negative Pressure Wound Therapy: Challenges, Novel Techniques, and Future Perspectives

Keenan, Corey; Obaidi, Noor; Neelon, Jamie; Yau, Irene; Carlsson, Anders H.; Nuutila, Kristo

doi:10.1089/wound.2023.0157

Cited by 3 publications

(2 citation statements)

References 86 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Adopting novel techniques across various fields often involves significant technical challenges and a steep learning curve. These hurdles may stem from the intricate nature of the techniques, the requirement for specialized equipment or training, and the potential for unforeseen complications during implementation [54][55][56]. For instance, recent negative pressure wound therapy (NPWT) advancements have introduced innovations in negative pressure delivery, pumps, interface dressings, adhesive dressings, and tubing technology.…”

Section: Technical Challenges and Learning Curve Associated With Nove...mentioning

confidence: 99%

“…Common issues include the failure to maintain negative pressure due to losing an airtight seal or tissue ingrowth into the interface dressing, leading to painful dressing changes and bleeding. Challenges like infection control and patient discomfort may also contribute to noncompliance with NPWT protocols [55].…”

Section: Technical Challenges and Learning Curve Associated With Nove...mentioning

confidence: 99%

See 1 more Smart Citation

Optimizing Acetabular Positioning: A Comprehensive Review of Contemporary Strategies in Total Hip Arthroplasty

Teja,

Shrivastava,

Choudhary

et al. 2024

Cureus

View full text Add to dashboard Cite

Total hip arthroplasty (THA) is a widely practiced surgical intervention to alleviate pain and reinstate functionality in individuals afflicted with hip joint pathology. The positioning of the acetabulum assumes paramount significance in determining the efficacy of THA, exerting profound influences on biomechanical dynamics, stability, and the durability of outcomes over time. This comprehensive review meticulously evaluates contemporary methodologies for optimizing acetabular positioning in THA, encompassing advanced technologies such as computer-assisted navigation systems, patient-specific instrumentation, robotic-assisted surgical approaches, image-based planning techniques, and intraoperative fluoroscopy. Crucially, key discoveries underscore the pivotal role of precise acetabular alignment in mitigating complications such as dislocation, component wear, and impingement. Moreover, the implications for clinical practice accentuate the imperative of continuous education and training to ensure effective deployment of sophisticated methodologies. Recommendations for furthering research and enhancing practice development underscore the necessity of scrutinizing long-term prognoses, assessing cost-effectiveness, and embracing technological innovations perpetually refining THA outcomes. Collaborative endeavors among researchers, practitioners, and industry stakeholders emerge as indispensable drivers of advancement in this domain, fostering an environment conducive to elevating the standard of care for individuals undergoing THA.

show abstract

Section: Technical Challenges and Learning Curve Associated With Nove...mentioning

confidence: 99%

Section: Technical Challenges and Learning Curve Associated With Nove...mentioning

confidence: 99%

Optimizing Acetabular Positioning: A Comprehensive Review of Contemporary Strategies in Total Hip Arthroplasty

Teja,

Shrivastava,

Choudhary

et al. 2024

Cureus

View full text Add to dashboard Cite

show abstract

Polymer‐ and Lipid‐Based Nanostructures Serving Wound Healing Applications: A Review

Cetin,

Mignon,

Van Vlierberghe

et al. 2024

Adv Healthcare Materials

View full text Add to dashboard Cite

Management of hard‐to‐heal wounds often requires specialized care that surpasses the capabilities of conventional treatments. Even the most advanced commercial products lack the functionality to meet the needs of hard‐to‐heal wounds, especially those complicated by active infection, extreme bleeding, and chronic inflammation. The review explores how supramolecular nanovesicles and nanoparticles—such as dendrimers, micelles, polymersomes, and lipid‐based nanocarriers—can be key to introducing advanced wound healing and monitoring properties to address the complex needs of hard‐to‐heal wounds. Their potential to enable advanced functions essential for next‐generation wound healing products—such as hemostatic functions, transdermal penetration, macrophage polarization, targeted delivery, and controlled release of active pharmaceutical ingredients (antibiotics, gaseous products, anti‐inflammatory drugs, growth factors)—is discussed via an extensive overview of the recent reports. These studies highlight that the integration of supramolecular systems in wound care is crucial for advancing toward a new generation of wound healing products and addressing significant gaps in current wound management practices. Current strategies and potential improvements regarding personalized therapies, transdermal delivery, and the promising critically evaluated but underexplored polymer‐based nanovesicles, including polymersomes and proteinosomes, for wound healing.

show abstract

Negative Pressure Smart Patch to Sense and Heal the Wound

Liu,

Zhao,

et al. 2024

Advanced Science

View full text Add to dashboard Cite

Negative pressure wound therapy (NPWT) offers significant advantages in terms of rate and time for healing through generating sub‐vacuum to draw out inflammatory exudate and promote wound closure. However, continuous drainage probably leads to healing delay due to the lack of information about the real status of the wound bed and the potential risk of infection. To address this concern, printed Negative Pressure Smart Patch (NPSP) is reported by integrating smart real‐time sensing acidity (infection) and glucose, and anti‐infection into NPWT systems. In addition, NPSP delivers vancomycin through chitosan porous microspheres under negative pressure to modulate wound healing. Compared with NPWT, NPSP projects a promising approach to removing bacteria, reducing local inflammation, and accelerating healing in a short period of time.

show abstract

Negative Pressure Wound Therapy: Challenges, Novel Techniques, and Future Perspectives

Cited by 3 publications

References 86 publications

Optimizing Acetabular Positioning: A Comprehensive Review of Contemporary Strategies in Total Hip Arthroplasty

Optimizing Acetabular Positioning: A Comprehensive Review of Contemporary Strategies in Total Hip Arthroplasty

Polymer‐ and Lipid‐Based Nanostructures Serving Wound Healing Applications: A Review

Negative Pressure Smart Patch to Sense and Heal the Wound

Contact Info

Product

Resources

About