The review presents data from the analysis of the literature on various options of using negative pressure wound therapy after abdominal-perineal extirpation of the rectum. We have selected 10 scientific papers for analysis, and no randomized trials have been found in the literature. The use of local negative pressure led to an acceleration of tissue repair and a decrease in complications in the perineal wound area. However, at the moment, the data presented in the literature are insufficient for an objective assessment of the effectiveness of the technique. It is necessary to conduct randomized trials to objectively evaluate the methodology.