Neglected etiologies of prolonged febrile illnesses in tropical and subtropical regions: A systematic review
Stefano Musumeci,
Alexandra Kruse,
François Chappuis
et al.
Abstract:Background
Febrile illnesses that persist despite initial treatment are common clinical challenges in (sub)tropical low-resource settings. Our aim is to review infectious etiologies of “prolonged fevers” (persistent febrile illnesses, PFI) and to quantify relative contributions of selected neglected target diseases with limited diagnostic options, often overlooked, causing inadequate antibiotic prescriptions, or requiring prolonged and potentially toxic treatments.
Methods
We performed a systematic review of… Show more
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