Neighborhood deprivation and warfarin, aspirin and statin prescription — A cohort study of men and women treated for atrial fibrillation in Swedish primary care

Carlsson, Axel C.; Wändell, Per; Gasevic, Danijela; Sundquist, Jan; Sundquist, Kristina

doi:10.1016/j.ijcard.2015.04.005

Cited by 25 publications

(30 citation statements)

References 40 publications

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“…We used neighborhood socioeconomic status as a proxy for lifestyle [38], and we used an area-based system to characterize the neighborhoods in which each individual resided in the present study [35,36]. Neighborhood socioeconomic status has also been shown to be associated with having cardiovascular pharmacotherapy prescribed according to guidelines [41]. The results in the present study were attenuated but still significant in men after adjustments for neighborhood socioeconomic status, and drug and alcohol abuse.…”

Section: Discussionmentioning

confidence: 68%

Psychiatric comorbidities in patients with hypertension – a study of registered diagnoses 2009–2013 in the total population in Stockholm County, Sweden

Sandström

Ljunggren

Wändell

et al. 2016

Journal of Hypertension

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Section: Discussionmentioning

confidence: 68%

Psychiatric comorbidities in patients with hypertension – a study of registered diagnoses 2009–2013 in the total population in Stockholm County, Sweden

Sandström

Ljunggren

Wändell

et al. 2016

Journal of Hypertension

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“…Prescribed cardiovascular drugs have also been shown to be in agreement with guidelines to a higher degree in high-SES neighbourhoods than in low-SES neighbourhoods 27. Yet, the results were still significant when we adjusted for neighbourhood goods and services including access to pharmacies and healthcare.…”

Section: Discussionmentioning

confidence: 85%

Neighbourhood socioeconomic status and coronary heart disease in individuals between 40 and 50 years

Carlsson

Holzmann

et al. 2016

Heart

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Objective The incidence of myocardial infarction (MI) has decreased in general but not among younger middle-aged adults. We performed a cohort study of the association between neighbourhood socioeconomic status (SES) at the age of 40 and risk of MI before the age of 50 years. Methods All individuals in Sweden were included in the year of their 40th birthday, if it occurred between 1998 and 2010. National registers were used to categorise neighbourhood SES into high, middle and low, and to retrieve information on incident MI and coronary heart disease (CHD). Cox regression models, adjusted for marital status, education level, immigrant status and region of residence, provided an estimate of the HRs and 95% CIs for MI or CHD. Results Out of 587 933 men and 563 719 women, incident MI occurred in 2877 (0.48%) men and 932 (0.17%) women; and CHD occurred in 4400 (0.74%) men and 1756 (0.31%) women during a mean follow-up of 5.5 years. Using individuals living in middle-SES neighbourhoods as referents, living in high-SES neighbourhoods was associated with lower risk of MI in both sexes (HR (95% CI): men: 0.72 (0.64 to 0.82), women: 0.66 (0.53 to 0.81)); living in low-SES neighbourhoods was associated with a higher risk of MI (HR (95% CI): men: 1.31 (1.20 to 1.44), women: 1.28 (1.08 to 1.50)). Similar risk estimates for CHD were found. Conclusions The results of our study suggest an increased risk of MI and CHD among residents from low-SES neighbourhoods and a lower risk in those from high-SES neighbourhoods compared with residents in middle-SES neighbourhoods.

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“…Individuals living in low SES neighbourhoods have a lower awareness of healthy life-style changes than individuals in high SES neighbourhoods (27), and have been shown to have an earlier onset of multi-morbidities (28). Moreover, they receive less optimal pharmacotherapy for their AF (29). Yet, the present results of a higher mortality in men with AF and subsequent depression remained significant after adjustments for neighbourhood SES, indicating that the neighbourhood SES does not explain the excess mortality.…”

Section: Discussionmentioning

confidence: 99%

Depression or anxiety and all-cause mortality in adults with atrial fibrillation – A cohort study in Swedish primary care

et al. 2016

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Objective Our aim was to study depression and anxiety in atrial fibrillation (AF) patients as risk factors for all-cause mortality in a primary care setting. Methods The study population included adults (n = 12 283) of 45 years and older diagnosed with AF in 75 primary care centres in Sweden. The association between depression or anxiety and all-cause mortality was explored using Cox regression analysis, with hazard ratios (HRs) and 95% confidence intervals (95% CIs). Analyses were conducted in men and women, adjusted for age, educational level, marital status, neighborhood socio-economic status (SES), change of neighborhood status and anxiety or depression, respectively, and cardiovascular co-morbidities. As a secondary analysis, background factors and their association with depression or anxiety were explored. Results The risk of all-cause mortality was higher among men with depression compared to their counterparts without depression even after full adjustment (HR = 1.28, 95% CI 1.08–1.53). For anxiety among men and anxiety or depression among women with AF, no associations were found. Cerebrovascular disease was more common among depressed AF patients. Conclusions Increased awareness of the higher mortality among men with AF and subsequent depression is called for. We suggest a tight follow-up and treatment of both ailments in clinical practice.

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Neighborhood deprivation and warfarin, aspirin and statin prescription — A cohort study of men and women treated for atrial fibrillation in Swedish primary care

Cited by 25 publications

References 40 publications

Psychiatric comorbidities in patients with hypertension – a study of registered diagnoses 2009–2013 in the total population in Stockholm County, Sweden

Psychiatric comorbidities in patients with hypertension – a study of registered diagnoses 2009–2013 in the total population in Stockholm County, Sweden

Neighbourhood socioeconomic status and coronary heart disease in individuals between 40 and 50 years

Depression or anxiety and all-cause mortality in adults with atrial fibrillation – A cohort study in Swedish primary care

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