Neoadjuvant treatment in locally advanced rectal cancer

Abstract

The optimal treatment for locally advanced rectal cancer remains an issue of debate. The surgery with total mesorectal excision (TME) still is the standard of care. In contrast to TME, the addition of adjuvant or neoadjuvant therapy is necessary in terms of local disease control and to increase of survival time. Here, we will review neoadjuvant treatment approach in rectal carcinoma.

Proceedings in oncology: Aren’t we back to the future?

“…Faysal Dane outlined the importance of HER-2 targeted therapies on gastric carcinomas [2]. Zuleyha Akgun and Esra Saglam reviewed their recent data and literature on neoadjuvant treatment in rectal carcinomas [3].…”