Neobladder overactivity; an equivalent to spontaneous rectal contraction

Sakakibara, Ryuji; Awa, Yusuke; Naya, Yukio; Tobe, Toyofusa; Uchiyama, Tomoyuki; Hattori, Takamichi

doi:10.1111/j.1442-2042.2007.01885.x

Cited by 4 publications

(2 citation statements)

References 10 publications

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“…However, short postoperative period time could not fully explain the voiding feature of all patients in this group, which accounted for approximately 40% of the entire cohort. Previous studies have described the presence of neobladder over-activity and the association with nocturnal incontinence and urge incontinence [ 19 , 20 ]. A recent study has shown the efficacy of intravesical botulinum toxin injection in the treatment of patients with neobladder over-activity and urinary incontinence [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

Cluster analysis identifies three urodynamic patterns in patients with orthotopic neobladder reconstruction

et al. 2017

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PurposeTo classify patients with orthotopic neobladder based on urodynamic parameters using cluster analysis and to characterize the voiding function of each group.Materials and methodsFrom January 2012 to November 2015, 142 patients with bladder cancer underwent radical cystectomy and Studer neobladder reconstruction at our institute. Of the 142 patients, 103 with complete urodynamic data and information on urinary functional outcomes were included in this study. K-means clustering was performed with urodynamic parameters which included maximal cystometric capacity, residual volume, maximal flow rate, compliance, and detrusor pressure at maximum flow rate. Three groups emerged by cluster analysis. Urodynamic parameters and urinary function outcomes were compared between three groups.ResultsGroup 1 (n = 44) had ideal urodynamic parameters with a mean maximal bladder capacity of 513.3 ml and mean residual urine volume of 33.1 ml. Group 2 (n = 42) was characterized by small bladder capacity with low compliance. Patients in group 2 had higher rates of daytime incontinence and nighttime incontinence than patients in group 1. Group 3 (n = 17) was characterized by large residual urine volume with high compliance. When we examined gender differences in urodynamics and functional outcomes, residual urine volume and the rate of daytime incontinence were only marginally significant. However, females were significantly more likely to belong to group 2 or 3 (P = 0.003). In multivariate analysis to identify factors associated with group 1 which has the most ideal urodynamic pattern, age (OR 0.95, P = 0.017) and male gender (OR 7.57, P = 0.003) were identified as significant factors.ConclusionsWhile patients with ileal neobladder present with various voiding symptoms, three urodynamic patterns were identified by cluster analysis. Approximately half of patients had ideal urodynamic parameters. The other two groups were characterized by large residual urine and small capacity bladder with low compliance. Young age and male gender appear to have a favorable impact on urodynamic and voiding outcomes in patients undergoing orthotopic neobladder reconstruction.

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Section: Discussionmentioning

confidence: 99%

Cluster analysis identifies three urodynamic patterns in patients with orthotopic neobladder reconstruction

et al. 2017

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“…In humans, replacing the esophagus or bladder with a colonic segment led to a loss of visceral sensation but preserved the colonic motility. 15…”

Section: Peripheral Nervesmentioning

confidence: 99%

Gastrointestinal Dysfunction in Multiple Sclerosis and Related Conditions

Sakakibara

2023

Semin Neurol

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Nervous system disorders may be accompanied by gastrointestinal (GI) dysfunction. Brain lesions may be responsible for GI problems such as decreased peristalsis (e.g., lesions in the basal ganglia, pontine defecation center/Barrington's nucleus), decreased abdominal strain (e.g., lesions in the parabrachial nucleus), hiccupping and vomiting (e.g., lesions in the area postrema), and appetite loss (e.g., lesions in the hypothalamus). Decreased peristalsis also may be caused by lesions of the spinal long tracts or the intermediolateral nucleus projecting to the myenteric plexus. This review addresses GI dysfunction caused by multiple sclerosis, neuromyelitis optica spectrum disorder, and myelin oligodendrocyte glycoprotein-associated disorder. Neuro-associated GI dysfunction may develop concurrently with brain or spinal cord dysfunction or may predate it. Collaboration between gastroenterologists and neurologists is highly desirable when caring for patients with GI dysfunction related to nervous system disorders, particularly since patients with these symptoms may visit a gastroenterologist prior to the establishment of a neurological diagnosis.

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Gastrointestinal dysfunction in movement disorders

Sakakibara

2021

Neurol Sci

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Neobladder overactivity; an equivalent to spontaneous rectal contraction

Cited by 4 publications

References 10 publications

Cluster analysis identifies three urodynamic patterns in patients with orthotopic neobladder reconstruction

Cluster analysis identifies three urodynamic patterns in patients with orthotopic neobladder reconstruction

Gastrointestinal Dysfunction in Multiple Sclerosis and Related Conditions

Gastrointestinal dysfunction in movement disorders

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