Neodymium-YAG laser photocoagulation versus multipolar electrocoagulation for the treatment of severely bleeding ulcers: a randomized comparison

Adverse events of upper GI endoscopy

“…233 Randomized, controlled trials using multipolar electrocautery or heater probe have reported rates of perforation as high as 2%. [234][235][236][237] The rate of perforation may be higher (Յ4%) with repeat heater probe treatment when performed within 24 to 48 hours of the initial session. 238 Induction or exacerbation of bleeding is a relatively common adverse event of thermal hemostasis, occurring in as many as 5% of cases.…”

“…238 Induction or exacerbation of bleeding is a relatively common adverse event of thermal hemostasis, occurring in as many as 5% of cases. 229,235,236,239 Although dual therapy with both epinephrine and a thermal modality or with 2 types of injectates is as effective as monotherapy with either a thermal technique or endoscopic clips, adverse events may be higher with dual therapy. 229,235 Endoscopic clips are the most commonly used mechanical device for endoscopic hemostasis.…”

Endoscopic Injection Therapy for Nonvariceal Upper Gastrointestinal Bleeding: Effective and Safe

“…Recently, however, the endoscope has been successfully used for therapeutic interventional purposes in patients with GI bleeding intractable to medical management [2,3,[6][7][8][9][10][11][12][13][14][15][16]. However, it is important to select the patients who need such procedures since in around 80% of the patients, the bleeding stops spontaneously [18,19].…”

“…While diagnostic endoscopy did not affect morbidity, mortality or the need for surgical intervention [4,5], therapeutic endoscopy, in contrast, has significantly reduced the complications of UGI bleeding [1,2,6,7]. The available and effective therapeutic modalities currently used for non-variceal UGI bleeding are: 1. thermal devices.…”

Laser probe coagulation of bleeding canine ulcers

“…Clear superiority of any one of these treatment methods has not, however, been demonstrated. Goff [6] and Rutgeerts et al [7] prospectively compared patients treated for bleeding by YAG laser with those treated with bipolar coagulation and found no significant differences in rebleeding or mortality between treatment groups. Sanowski [8] reviewed endoscopic methods for treatment of gastrointestinal bleeding and showed that lasers are more costly and cumbersome for treatment of gastrointestinal hemorrhage than are other currently available systems.…”