Neolignans from Flower Buds of Magnolia fargesii and their Antitobacco Mosaic Virus Activities

Abstract

A new neolignan, fargesilignan A (1), together with five known neolignans (2-6), were isolated from the flower buds of Magnolia fargesii. The structures of 1-6 were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1-6 were tested for their antitobacco mosaic virus activities. Compounds 2 and 5 (20 µM) showed moderate antitobacco mosaic virus activity with inhibition rates of 14.5 and 22.2 %.