Neonatal aortic thrombosis: Recent experience

Antithrombotic Therapy in Neonates and Children

“…336 Embolic events are also reported, and UAC thrombosis has been linked to the development of NEC. 337,338 Longer-term outcomes include death, 339 persistent renovascular hypertension, and lower-limb growth abnormalities. 340 Six RCTs addressed the use of low-dose heparin infusions in neonates with UACs, [341][342][343][344][345][346] which was the subject of a systematic review by Barrington.…”

Single-Dose Captopril Scintigraphy in the Neonate with Renovascular Hypertension: Prediction of Renal Failure, a Side Effect of Captopril Therapy

“…However, serious morbidity and mortality have been attrib uted to thromboembolic catheter complica tions including renovascular hypertension (RVH) [1,2], RVH frequently complicates renal infarction or renal ischemia from thromboembolism of a branch or the entire renal artery(ies) or of the aorta [3], and is the result of hypersecretion of renin from the kidney(s) as a compensatory mechanism to maintain glomerular filtration [4,5], The converting enzyme inhibitors (CEI), capto pril (CAP) and enalapril, are effective in hyperreninemic hypertension and have been introduced in the treatment of neonatal RVH [6]. However, in patients with RVH due to an ischemic single kidney or with RVH due to bilateral renal ischemia from renal artery stenosis, treatment with CEI may induce renal failure by decompensating the ischemic kidney(s) [7,8], This complica tion is reversible and persists while the drug is circulating.…”

Radiology Casebook

“…Significant complications, such as thrombosis, embolism, hemorrhage, vascular perforation, sepsis, vasospasm, and thoracic and abdominal aortic aneurysms have been reported. [2][3][4][5][6][7][8] Wigger et al 9 reported the first case of an aneurysm associated with UAC in 1970; since then, 49 additional cases have been reported in the literature. 10 -22 An extensive review of all of these cases was performed.…”