Neonatal Appendicitis Presenting as Bilious Emesis and Septic Shock

Umscheid, Jacob; Nguyen, Khai M; Vasudeva, Rhythm; Agasthya, Nisha

doi:10.17161/kjm.vol1414990

Cited by 2 publications

(4 citation statements)

References 14 publications

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“…With cross‐referencing, eight additional eligible articles were identified. In total, 131 articles were included in this systematic review 3,6,12–140 . Figure 1 provides the PRISMA flowchart.…”

Section: Resultsmentioning

confidence: 99%

“…In total, 131 articles were included in this systematic review. 3 , 6 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 ...…”

Section: Resultsmentioning

confidence: 99%

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Appendicitis and its associated mortality and morbidity in infants up to 3 months of age: A systematic review

The,

Derikx

et al. 2023

Health Science Reports

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Background and AimsAlthough appendicitis is rare in young infants, the reported mortality is high. Primary aim of this systematic review was to provide updated insights in the mortality and morbidity (postoperative complications, Clavien‐Dindo grades I–IV) of appendicitis in infants ≤3 months of age. Secondary aims comprised the evaluation of patient characteristics, diagnostic work‐up, treatment strategies, comorbidity, and factors associated with poor outcome.MethodsThis systematic review was reported according to the PRISMA statement with a search performed in Pubmed, Embase and Web of Science (up to September 5th 2022). Original articles (published in English ≥1980) reporting on infants ≤3 months of age with appendicitis were included. Both patients with abdominal appendicitis and herniated appendicitis (such as Amyand's hernia) were considered. Data were provided descriptively.ResultsIn total, 131 articles were included encompassing 242 cases after identification of 4294 records. Overall, 184 (76%) of the 242 patients had abdominal and 58 (24%) had herniated appendicitis. Two‐hundred (83%) of the patients were newborns (≤28 days) and 42 (17%) were infants between 29 days and ≤3 months of age. Either immediate, or after initial conservative treatment, 236 (98%) patients underwent surgical treatment. Some 168 (69%) patients had perforated appendicitis. Mortality was reported in 20 (8%) patients and morbidity in an additional 18 (8%). All fatal cases had abdominal appendicitis and fatal outcome was relatively more often reported in newborns, term patients, patients with relevant comorbidity, nonperforated appendicitis and those presented from home.ConclusionMortality was reported in 20 (8%) infants ≤3 months of age and additional morbidity in 18 (8%). All patients with fatal outcome had abdominal appendicitis. Several patient characteristics were relatively more often reported in infants with poor outcome and adequate monitoring, early recognition and prompt treatment may favour the outcome.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Appendicitis and its associated mortality and morbidity in infants up to 3 months of age: A systematic review

The,

Derikx

et al. 2023

Health Science Reports

View full text Add to dashboard Cite

show abstract

“…Anatomically, appendicitis is less likely to occur in those under one year of age. At this age, the appendix is funnel-shaped with a wider opening, generally preventing obstruction [3]. However, the omentum at this time is underdeveloped, which often leads to rapid peritonitis due to the inability to handle infection if perforation does occur [3].…”

Section: Discussionmentioning

confidence: 99%

“…At this age, the appendix is funnel-shaped with a wider opening, generally preventing obstruction [3]. However, the omentum at this time is underdeveloped, which often leads to rapid peritonitis due to the inability to handle infection if perforation does occur [3]. When appendicitis does occur in neonates, the thinner appendix wall makes these patients especially susceptible to perforation, with 70% of patients aged less than three years developing perforation within 48 hours of symptom onset [4].…”

Section: Discussionmentioning

confidence: 99%

Appendicitis in a Six-Month-Old Child With Coincidental Pneumonia

Deskins¹,

Abbey²,

Vozar³

et al. 2023

Cureus

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Appendicitis is an exceedingly uncommon diagnosis in infancy and, thus, is typically not considered a differential diagnosis for this population. Its atypical presentation, with a wide range of clinical manifestations, creates a diagnostic challenge for physicians. Along with this, a patient's inability to articulate their pain adds another layer of diagnostic challenge. Here, we present the case of a six-monthold infant with a complicated hospital course of pneumonia and subsequent ileus, who was later found to have appendicitis with a surrounding abscess.

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Neonatal Appendicitis Presenting as Bilious Emesis and Septic Shock

Cited by 2 publications

References 14 publications

Appendicitis and its associated mortality and morbidity in infants up to 3 months of age: A systematic review

Appendicitis and its associated mortality and morbidity in infants up to 3 months of age: A systematic review

Appendicitis in a Six-Month-Old Child With Coincidental Pneumonia

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