Neonatal asphyxia and associated factors among neonates on labor ward at debre-tabor general hospital, Debre Tabor Town, South Gonder, North Centeral Ethiopia

Necho, Worku; Yesuf, Ansha

doi:10.15406/ipcb.2018.04.00128

Cited by 1 publication

(1 citation statement)

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“…In the current meta-analysis, 17,091 study participants were represented. The prevalence of perinatal asphyxia reported was between 3.1% (18) and 47.5% (19) and the sample size of the studies ranged from 154 (20) to 3684 (21).…”

Section: Explanation For Included Studiesmentioning

confidence: 99%

Prevalence of perinatal asphyxia and its associated factors in Ethiopia; A systematic review and meta-Analysis

Assemie¹,

Tizazu²,

Labata³

et al. 2019

Preprint

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Background: Perinatal asphyxia(PNA) is a severe health problem and main cause of neonatal mortality and morbidity worldwide. In Ethiopia, there are many studies conducted on PNA characterized by replete of inconsistent; unavailability of nation wide study to determines the prevalence of PNA and its determinants is an important gap. The aim of this study is to develop national consensus on pooled prevalence and associated factor key reports to enhance the quality and consistency of the evidence on perinatal asphyxia. Method: Systematic review and meta-analysis using computerized databases; searches were performed to locate all articles on the prevalence of perinatal asphyxia. Databases included were Pub Med, Cochran library, Google Scholar, Scopus and Science Direct systematically between 2014 and April 2019. All identified studies reporting the prevalence of PNA in Ethiopia were pooled. Two independent authors extracted the data using a standardized data extraction tool. The Cochrane Q test statistics and I2 tests were used to assess the heterogeneity of the studies. Random-effects model was used to calculate pooled estimates and determinant factor of PNA in Stata/se version-14. Result: The prevalence of PNA reported from fifteen studies was in the range of 3.1 to 47.5%. The pooled occurrence of PNA in Ethiopia based on 15 articles with a sample size of 17,091 was 21.1% (95% CI: 14, 28). There was high heterogeneity observed (I2 = 99.4%, p <0.001). Thus, Subgroup analysis in the study area was computed .Thus, the highest prevalence (40.4%) was observed from Oromia region and the lowest 8% noted from Dire Dawa city administration. Pooled odd ratio estimates from included studies revealed prolonged labour (OR=3.7, 95% CI 2.4, 5.7), low birth weight (OR=6.5, 95% CI 4.0, 10.3), and Meconium stained liquor (OR=6.6, 95% CI: 4.4, 10.1) are significant risk factors of perinatal asphyxia. Conclusion: In this review, prolonged labour, meconium stained liquor and low birth weight are significantly associated with perinatal asphyxia. Therefore, improve facility-based intra partum care and quality neonatal resuscitation service through capacity building for health professionals is needed.

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Section: Explanation For Included Studiesmentioning

confidence: 99%