Neonatal aspiration syndrome due to vernix caseosa

Ohlsson, Arne; Cumming, William A.; Najjar, Haitham

doi:10.1007/bf02388611

Cited by 11 publications

(8 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 The clinical presentation and radiological changes seen in this case suggest that, when inhaled, maternal blood produces similar effects to other particulate or toxic matter such as meconium, vernix and cellular debris. [2][3][4] Pulmonary haemorrhage is an important differential diagnosis but clinical and radiological features are quite distinct. 7 It is usually associated with severe respiratory compromise, efflux of haemorrhage fluid from the airways, post-haemorrhagic coagulopathy and thrombocytopenia.…”

Section: Discussionmentioning

confidence: 99%

“…1 Respiratory distress in the newborn infant can occur owing to aspiration of a variety of amniotic fluid contaminants such as meconium, vernix caseosa and cellular debris. [2][3][4] It is suggested that aspiration of blood or blood-stained amniotic fluid could also cause aspiration syndrome in neonates. 1,5 However, very few cases have been reported.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Maternal blood aspiration: an unusual cause of respiratory distress in a neonate

Deodhar¹,

Pharande²,

Vaidya³

et al. 2006

Annals of Tropical Paediatrics

View full text Add to dashboard Cite

Maternal blood aspiration is an unusual cause of respiratory distress in neonates. It is occasionally seen in babies born to mothers with antepartum haemorrhage (APH). We report a term neonate with a history of maternal APH who developed respiratory distress soon after birth with a radiological appearance compatible with aspiration syndrome. The infant required ventilation for 36 hours. The aspirated blood was the mother's.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Maternal blood aspiration: an unusual cause of respiratory distress in a neonate

Deodhar¹,

Pharande²,

Vaidya³

et al. 2006

Annals of Tropical Paediatrics

View full text Add to dashboard Cite

show abstract

“…Vernix caseosa has been implicated in the causation of neonatal aspiration syndrome8283 and vernix caseo-granulomatous meningitis 84. Hence, pregnant women with a diffuse pattern of high-level echoes in prenatal ultrasonography, suggesting the presence of massive vernix caseosa, should be shifted to a well-equipped institution for delivery.…”

Section: Diagnostic and Prognostic Implications Of Vernix Caseosamentioning

confidence: 99%

Unraveling the mystery of vernix caseosa

Singh

Archana

2008

Indian J Dermatol

View full text Add to dashboard Cite

Vernix caseosa is a white, creamy, naturally occurring biofilm covering the skin of the fetus during the last trimester of pregnancy. Vernix coating on the neonatal skin protects the newborn skin and facilitates extra-uterine adaptation of skin in the first postnatal week if not washed away after birth. It consists of water-containing corneocytes embedded in a lipid matrix. The strategic location of the vernix on the fetal skin surface suggests participation in multiple overlapping functions required at birth, such as barrier to water loss, temperature regulation, and innate immunity. Vernix seems to perform various integral roles during transition of the fetus from intra-uterine to extra-uterine life. It has also found various interesting diagnostic and prognostic implications in this arena. Thus, it continues to be an intriguing topic of interest among the medical fraternity to understand its detailed biology and function in the fetus and also to put its naturally endowed characteristics to use in the adult population.

show abstract

“…Only one case with vernix caseosa aspiration syndrome has been reported previously [3] . In that case, the male infant was born vaginally at 41 weeks of gestation with Apgar scores of 2 and 7 at 1 and 5 min, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…Only one aspiration syndrome caused by an airway obstruction of vernix caseosa has been previously reported [3] . In that case, the infant's life was saved with intensive care.…”

Section: Introductionmentioning

confidence: 99%

Management for Neonatal Aspiration Syndrome Caused by Vernix caseosa

Nishijima

Shukunami²,

Inoue³

et al. 2005

Fetal Diagn Ther

View full text Add to dashboard Cite

Objective: To clarify resuscitation methods against the lethal vernix caseosa aspiration syndrome. Method: A single case report with a literature review. Results: Our case report was associated with aspiration syndrome caused by an airway obstruction of vernix caseosa: a proteolipid biofilm synthesized by the fetus. A 23-year-old woman normally delivered a mature infant at term. The infantile oral cavity was filled with numerous aggregates of vernix caseosa. Two hours after his birth, the infant died from respiratory insufficiency. We discuss the difference between management of our case and the previously reported case.Conclusion: Pregnant women with a diffuse pattern of high-level echoes in prenatal ultrasonography, suggesting the presence of massive vernix caseosa, should be transferred to a well-equipped institution that can administer inhaled nitric oxide and extracorporeal membrane oxygenation.

show abstract

Neonatal aspiration syndrome due to vernix caseosa

Cited by 11 publications

References 8 publications

Maternal blood aspiration: an unusual cause of respiratory distress in a neonate

Maternal blood aspiration: an unusual cause of respiratory distress in a neonate

Unraveling the mystery of vernix caseosa

Management for Neonatal Aspiration Syndrome Caused by Vernix caseosa

Contact Info

Product

Resources

About