Neonatal blue light phototherapy increases café-au-lait macules in preschool children

Abstract

In this study, NBLP had no significant influence on the development of melanocytic nevi, but on café-au-lait macules which was a new finding. Differences with comparable studies regarding age, differentiation between nevi and other pigmented lesions as well as dose and type of NBLP need to be taken into account for further investigations.

Neonatal Blue Light Phototherapy and Melanocytic Nevus Count in Children: A Systematic Review and Meta‐Analysis of Observational Studies

“…Whether NBLP predisposes to the development of melanocytic nevi later in life is unclear. Various epidemiologic studies have investigated the association between NBLP exposure and the development of melanocytic nevi in childhood, but the results were inconsistent . The goal of the current study was to conduct a systematic review and meta‐analysis to quantitatively assess the impact of prior NBLP exposure on the melanocytic nevus count in children.…”

Phototherapy as a Treatment for Dermatological Diseases, Cancer, Aesthetic Dermatologic Conditions and Allergenic Rhinitis in Adult and Paediatric Medicine

“…Neonatal blue light phototherapy (NBLP) is an effective treatment for hyperbilirubinemia. However, a significantly higher prevalence of hyperpigmented skin patches was found in children treated with NBLP than in children without NBLP [ 31 ]. Further research would be necessary to fully understand the effectiveness of NBLP treatment.…”