Neonatal erythropoiesis and subsequent anemia in HIV-positive and HIV-negative Zimbabwean babies during the first year of life: a longitudinal study

Miller, M. F.; Humphrey, Jean H.; Iliff, Peter; Malaba, Lucie C.; Mbuya, Nkosinathi Vusizihlobo; Stoltzfus, Rebecca J.

doi:10.1186/1471-2334-6-1

Cited by 120 publications

(98 citation statements)

References 51 publications

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“…4 Hemoglobin (Hb) was measured for all women enrolled from Oct 1, 1998 onwards (about 60% of the total sample). 9 Baseline HIVpositive mothers were retested at their next visit to confirm the diagnosis; baseline negative mothers were retested at every subsequent blood draw. For all infants born to HIVpositive mothers, cell pellets (Roche Diagnostics Systems, Alameda, CA) and plasma were prepared from whole blood collected at baseline and follow-up visits and stored at -70°C.…”

Section: Methodsmentioning

confidence: 99%

Child Mortality According to Maternal and Infant HIV Status in Zimbabwe

Marinda

Humphrey

Iliff

et al. 2007

Pediatric Infectious Disease Journal

283

281

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Perinatally infected infants are at particular risk of death between 2 and 6 months: cotrimoxazole prophylaxis and early pediatric HAART should be scaled up. Uninfected infants of infected mothers have at least twice the mortality risk of infants born to uninfected mothers: all HIV-exposed infants should be targeted with child survival interventions. HIV-positive mothers with more advanced disease are not only more likely to infect their infants, but their infants are more likely to die, whether infected or not: provision of antiretroviral treatment to pregnant and lactating women is an urgent need for both mothers and their children.

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Section: Methodsmentioning

confidence: 99%

Child Mortality According to Maternal and Infant HIV Status in Zimbabwe

Marinda

Humphrey

Iliff

et al. 2007

Pediatric Infectious Disease Journal

283

281

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“…Skin infection has also been documented after exposure to wading pools, public baths or tap water [10,11,12,13,14,15,16,17,18]. …”

Section: Discussionmentioning

confidence: 99%

<i>Mycobacterium abscessus</i> Skin Infection after Tattooing: First Case Report and Review of the Literature

Bechara¹,

Macheras

Heym

et al. 2010

Dermatology

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Mycobacterium abscessus is a species of rapidly growing mycobacteria (RGM). This species can cause skin and soft tissue infections after trauma or surgical procedures, pulmonary infections and disseminated diseases in immunocompromised patients. It has been rarely documented after tattoo procedures. Herein we describe the case of a 51-year- old man who presented with erythematous papules over a tattoo on the back 10 days after a tattoo session. Culture revealed M. abscessus. Tattoo infections, clinical features and treatment options due to RGM are reviewed.

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“…Regarding exclusive breast-feeding, although feeding infants with iron-fortified formula is associated with high iron stores, formula feeding is not recommended for most infants, especially in low-income countries, which are the focus of this symposium. Where formula is not widely available or is often not used properly, infants who are exclusively breast-fed have better iron status than those who are breast-fed but not exclusively (11,12). See the article by Dr. Chaparro in this symposium (13).…”

Section: Introductionmentioning

confidence: 94%

Research Needed to Strengthen Science and Programs for the Control of Iron Deficiency and Its Consequences in Young Children

Stoltzfus

2008

The Journal of Nutrition

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The purpose of this article is to highlight critical research needs for the effective prevention and control of iron deficiency and its consequences in children living in low-income countries. Four types of research are highlighted: The first involves scaling up interventions that we know are effective, namely iron supplementation of pregnant women, delayed cord clamping at delivery, immediate and exclusive breast-feeding, and continued exclusive breast-feeding for approximately 6 mo. The second entails evaluation research of alternative interventions that are likely to work, to find the most cost-effective strategies for a given social, economic, and epidemiological context. This research is especially needed to expand the implementation of appropriate complementary feeding interventions. In this area, research needs to be designed to provide causal evidence, to measure cost-effectiveness, and to measure potential effect modifiers. The third is efficacy research to discover promising practices where we lack proven interventions. Examples include how to detect infants younger than 6 mo who are at high risk of iron deficiency, efficacious and safe interventions for those young high-risk infants, and best protocols for the treatment of severe anemia. The fourth includes basic research to elucidate physiological processes and mechanisms underlying the risks and benefits of supplemental iron for children exposed to infectious diseases, especially malaria. Strategic research in all 4 areas will ensure that interventions to control pediatric iron deficiency are integrated into national programs and global initiatives to make pregnancy safer, reduce newborn deaths, and promote child development, health, and survival.

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Neonatal erythropoiesis and subsequent anemia in HIV-positive and HIV-negative Zimbabwean babies during the first year of life: a longitudinal study

Abstract: Background: Anemia is common in HIV infection and independently associated with disease progression and mortality. The pathophysiology of HIV-related anemia is not well understood especially in infancy.

Cited by 120 publications

References 51 publications

Child Mortality According to Maternal and Infant HIV Status in Zimbabwe

Child Mortality According to Maternal and Infant HIV Status in Zimbabwe

<i>Mycobacterium abscessus</i> Skin Infection after Tattooing: First Case Report and Review of the Literature

Research Needed to Strengthen Science and Programs for the Control of Iron Deficiency and Its Consequences in Young Children

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