Neonatal gonococcal arthritis after negative prenatal screening and despite conjunctival prophylaxis

Babl, Franz E; Ram, Sanjay; Barnett, Elizabeth D.; Rhein, Lawrence; Carr, Eileen M.; Cooper, Ellen

doi:10.1097/00006454-200004000-00017

Cited by 23 publications

(3 citation statements)

References 28 publications

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“…Disseminated gonococcal disease may present as septic arthritis (most commonly), meningitis, or sepsis. Gonococcal arthritis in the neonate can present anywhere from 1 to 4 weeks of life, and multiple joints may be affected [25].…”

Section: Clinical Featuresmentioning

confidence: 99%

Sexually Transmitted Infections in Pregnant Women: Integrating Screening and Treatment into Prenatal Care

Lochner

Maraqa

2018

Pediatr Drugs

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Chlamydia, gonorrhea, and syphilis continue to be significant burdens to the health of pregnant women and their children despite easy and effective guidance for screening and treatment. Specific guidelines exist for screening for these infections as well as treatment and follow-up. In this article, we review the epidemiology of chlamydia, gonorrhea, and syphilis. Testing methodology is also reviewed as molecular-based techniques have replaced culture as the current gold standard tests of choice for chlamydia and gonorrhea. The nontreponemal and treponemal serologic diagnostic and screening approach to syphilis has undergone less change. Treatment for gonorrhea includes a one-time dose of parenteral ceftriaxone and oral azithromycin. This treatment regimen not only addresses the possible gonococcal resistance seen in recent years but also treats chlamydia, which may present similarly or co-infect the same patient. Syphilis treatment in both pregnant women and their infected neonates remains with penicillin G formulations. It is crucial to establish close follow-up evaluation for the pregnant woman infected with these sexually transmitted infections to ensure adequate treatment and help prevent perinatal spread of the infection.

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Section: Clinical Featuresmentioning

confidence: 99%

Sexually Transmitted Infections in Pregnant Women: Integrating Screening and Treatment into Prenatal Care

Lochner

Maraqa

2018

Pediatr Drugs

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“…In the pre-antibiotic era, the most common cause of septic arthritis was gonococcal septic arthritis caused by Neisseria gonorrhoeae [21]. Among young sexually active adults, N. gonorrhoeae remains the most common causative organism.…”

Section: Microbiologymentioning

confidence: 99%

Septic arthritis in immunocompetent and immunosuppressed hosts

Wang

Tambyah

2015

Best Practice & Research Clinical Rheumatology

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“…Maternal screening and antibiotic prophylaxis of the eyes does not ensure that the newborn may not acquire invasive GC infection [16], and gonococcal colonization of the oropharynx or gastric fluid occurs relatively frequently in exposed infants [17]. Because of this potential failure of prophylaxis in maternal infection, infants born to mothers with known GC infections should be treated with a single parenteral dose of a third-generation cephalosporin [18•].…”

Section: Neonatal Gcmentioning

confidence: 99%

Extragenital manifestations of Neisseria gonorrhoeae

Spencer

Bash

2006

Curr Infect Dis Rep

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Neisseria gonorrhoeae is a common cause of genitourinary sexually transmitted infections. N. gonorrhoeae is an obligate human pathogen that has evidence of tissue-specific host interactions and diverse extragenital manifestations of infection both in adult and pediatric populations. The clinical presentation of extragenital gonorrhea, diagnostic methods, treatment and preventive measures are reviewed.

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Neonatal gonococcal arthritis after negative prenatal screening and despite conjunctival prophylaxis

Cited by 23 publications

References 28 publications

Sexually Transmitted Infections in Pregnant Women: Integrating Screening and Treatment into Prenatal Care

Sexually Transmitted Infections in Pregnant Women: Integrating Screening and Treatment into Prenatal Care

Septic arthritis in immunocompetent and immunosuppressed hosts

Extragenital manifestations of Neisseria gonorrhoeae

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