Neonatal Jaundice and Disorders of Bilirubin Metabolism

Gourley, Glenn R.

doi:10.1017/cbo9780511547409.015

Cited by 5 publications

(6 citation statements)

References 475 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The typical dark brown pigment which is visualized as coarse lipofuscin-like hepatocellular granules accumulates in the lysosomes of hepatocytes. 3 These were seen in our eight-week-old patient and they were noticed at an earlier age in a previous case report. 8 Their presence was taken as a definitive for DJS diagnosis.…”

Section: Case Reportsupporting

confidence: 68%

“…It is shown that viral hepatitis causes complete disappearance of pigment with subsequent slow reaccumulation. 3 In experimental animals, the renal histopathology study revealed glomerular lesions with mesangial expansion and proliferation. Furthermore, microhistopathological studies showed renal changes like IgA nephropathy, but such changes have not been described in humans.…”

Section: Case Reportmentioning

confidence: 99%

“…2 Our patient presented with jaundice in the neonatal period, which persisted for three months. Several cases of neonatal jaundice due to DJS have been reported in the international literature, 3,4 mostly with mild jaundice, but one case was reported to have severe cholestasis. 4 Usually DJS presents with recurrent jaundice in older children or adults.…”

Section: Case Reportmentioning

confidence: 99%

“…3 After the immediate peak, the hepatocytes take up the dye normally and the level declines. But when the conjugated dye starts refluxing back from hepatocytes into the blood, the second peak appears around 90 minutes onwards.…”

Section: Case Reportmentioning

confidence: 99%

See 3 more Smart Citations

Dubin-Johnson Syndrome in a Saudi Neonate

Nadroo¹,

Alzaben

Bilan³

et al. 1996

Ann Saudi Med

View full text Add to dashboard Cite

Section: Case Reportsupporting

confidence: 68%

Section: Case Reportmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

See 2 more Smart Citations

Dubin-Johnson Syndrome in a Saudi Neonate

Nadroo¹,

Alzaben

Bilan³

et al. 1996

Ann Saudi Med

View full text Add to dashboard Cite

“…Other important reason for hyperbilirubinemia in some infants is excess production of bilirubin from conditions that have increased red blood cell breakdown. It can occur in sick babies with infection or in babies with hypothyroidism, neonatal hepatitis or biliary atresia (4).…”

Section: Introductionmentioning

confidence: 99%

Maternal Perception about Neonatal Jaundice in Eastern Nepal: A Qualitative Study

Dharel

Bhattarai

2017

Health Prospect

View full text Add to dashboard Cite

Tweetable abstract: Perception of mothers about jaundice in newborn babies reflects their misconception and experience and also their family or societal belief.This is an open access article distributed on the terms of Creative Commons Attribution 3.0 license. This work may be freely reproduced, distributed, transmitted, modified, or otherwise used provided that the original work is properly cited. Author e-mails are available at the end of the article. AbstractBackground: Jaundice is a common problem in newborn babies and mothers have different misconceptions about it in Nepal. This study was conducted to explore mother's perception about the causes, recognition, management and outcome of neonatal jaundice. Methodology:In-depth interviews were conducted with 32 mothers of infants under six months of age with a history of jaundice in the neonatal period attending the outpatient department of Ilam District Hospital. Audio-taped data were transcribed and analyzed thematically.Results: Most of the mothers recognized jaundice in babies from yellow skin but some noticed it after being alerted by health workers or other people. They perceived jaundice in neonates as a serious condition. However, they were unclear about the cause and attributed it to breach in food restrictions, lack of hygiene or effect of evil spirits. Foods consumed by mothers during and after pregnancy were of concern, not only as a cause but also a remedial measure of jaundice. They usually resorted to traditional measures of avoiding certain foods and reported that health workers did not offer specific remedies and that some health workers even approved such practices. The perceptions of mothers were greatly influenced by family and societal beliefs and practices such as applying oil, sunbathing or avoiding various foods by mothers, often irrespective of advice from health workers. Mother-in-law and the health worker have had the prominent influence in mother's perception. Conclusion:The perceptions of mothers regarding recognition, seriousness, causes and treatment of jaundice in their newborn babies were mostly guided by their own misconceptions and experiences. However, the family and societal beliefs apparently had a big influence.

show abstract

Bile Secretion and Cholestasis

Feranchak

2015

Yamada' S Textbook of Gastroenterology

View full text Add to dashboard Cite

Neonatal Jaundice and Disorders of Bilirubin Metabolism

Cited by 5 publications

References 475 publications

Dubin-Johnson Syndrome in a Saudi Neonate

Dubin-Johnson Syndrome in a Saudi Neonate

Maternal Perception about Neonatal Jaundice in Eastern Nepal: A Qualitative Study

Bile Secretion and Cholestasis

Contact Info

Product

Resources

About