Neonatal lupus erythematosus: Report of a case with cutaneous, hematological and hepatobiliary findings

Abstract

Neonatal lupus erythematosus is an autoimmune disorder mainly affecting the heart and skin. It is the most common cause of congenital heart block. In addition, hematological, hepatobiliary and neurological involvement may occur. Herein, we report a 23-day-old infant presented with annular, erythematous, and scaly and atrophic lesions on the face and trunk. Based on the clinical, laboratory and histopathological findings, she was diagnosed as neonatal lupus erythematosus. Neonatal lupus eryhtematosus should be considered in infants presenting with annular skin lesions, and we present this case to highlight the value of high index of clinical suspicion in diagnosis.

An Isolated Thrombocytopenia in a Newborn

“…6 Noncardiac images usually resolve with the clearance of maternal autoantibodies, which in most cases is complete by the ninth month of life. 7 It is common for children with neonatal lupus not to express the disease fully but rather to have only 1 or 2 organ systems involved. 8 Hematological abnormalities usually occur in conjunction with either a cardiac or a cutaneous involvement but may be exceptionally isolated.…”

Congenital scars: a rare presentation of neonatal lupus

“…Neonatal LE typically presents with an annular scaly rash, predominantly over the head and upper trunk, the mean age of presentation being 6 weeks. Presence of predominantly atrophic lesions at birth, is an unusual presentation, rarely described in literature 1–3. But, it is important to consider this rare presentation for the prognostic implications it has for the baby and the mother.…”