Neonatal meningitis due to Lactobacillus

Broughton, Robert A.; Gruber, William C.; Haffar, Anan A. M.; Baker, Carol J.

doi:10.1097/00006454-198309000-00012

Cited by 46 publications

(20 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cases of serious infection have occurred and been reported in the literature. 10,[118][119][120][121][122][123][124][125] Patients at risk would be those who are immunocompromised, including ill preterm neonates, and/or children who have intravenous catheters or other indwelling medical devices. In most cases, the offending organism that caused the sepsis seems to have stemmed from bacteria from the individual's own endogenous flora.…”

Section: Safety Of Probiotics and Prebiotics In Infants And Childrenmentioning

confidence: 99%

“…Neonatal sepsis and meningitis that were apparently associated with the administration of a probiotic supplement were also reported. 118,120 A recent report focused on probiotic tolerance and safety in healthy term infants who were randomly assigned to be given a high-dose probiotic formula, a low-dose probiotic formula, or control formula for 18 months. 35 There were no apparent reported adverse events.…”

Section: Safety Of Probiotics and Prebiotics In Infants And Childrenmentioning

confidence: 99%

See 1 more Smart Citation

Probiotics and Prebiotics in Pediatrics

Thomas¹,

Greer²

2010

Pediatrics

357

220

View full text Add to dashboard Cite

This clinical report reviews the currently known health benefits of probiotic and prebiotic products, including those added to commercially available infant formula and other food products for use in children. Probiotics are supplements or foods that contain viable microorganisms that cause alterations of the microflora of the host. Use of probiotics has been shown to be modestly effective in randomized clinical trials (RCTs) in (1) treating acute viral gastroenteritis in healthy children; and (2) preventing antibiotic-associated diarrhea in healthy children. There is some evidence that probiotics prevent necrotizing enterocolitis in very low birth weight infants (birth weight between 1000 and 1500 g), but more studies are needed. The results of RCTs in which probiotics were used to treat childhood Helicobacter pylori gastritis, irritable bowel syndrome, chronic ulcerative colitis, and infantile colic, as well as in preventing childhood atopy, although encouraging, are preliminary and require further confirmation. Probiotics have not been proven to be beneficial in treating or preventing human cancers or in treating children with Crohn disease. There are also safety concerns with the use of probiotics in infants and children who are immunocompromised, chronically debilitated, or seriously ill with indwelling medical devices. Prebiotics are supplements or foods that contain a nondigestible food ingredient that selectively stimulates the favorable growth and/or activity of indigenous probiotic bacteria. Human milk contains substantial quantities of prebiotics. There is a paucity of RCTs examining prebiotics in children, although there may be some long-term benefit of prebiotics for the prevention of atopic eczema and common infections in healthy infants. Confirmatory well-designed clinical research studies are necessary.

show abstract

Section: Safety Of Probiotics and Prebiotics In Infants And Childrenmentioning

confidence: 99%

Section: Safety Of Probiotics and Prebiotics In Infants And Childrenmentioning

confidence: 99%

Probiotics and Prebiotics in Pediatrics

Thomas¹,

Greer²

2010

Pediatrics

357

220

View full text Add to dashboard Cite

show abstract

“…In these cases, CSF inoculation was done on either sheep blood or chocolate agar plates incubated at 37°C in a reduced CO 2 environment. 31 All blood and CSF cultures were followed beyond 48 hours of inoculation.…”

Section: Surveillance For Nimentioning

confidence: 99%

Prophylactic Probiotics to Prevent Death and Nosocomial Infection in Preterm Infants

et al. 2012

View full text Add to dashboard Cite

“…Molecular DNA fingerprinting confirmed that the LGG probiotic supplement was the bacterial isolate from the infant. Neonatal sepsis and meningitis that were apparently associated with the administration of a probiotic supplement were also reported [103,104]. Children with abnormal immune function, premature infants, and those with indwelling central lines should use these products with caution, because many species such as Lactobacilli, streptococci, and enterococci are potential opportunistic pathogens.…”

Section: Safetymentioning

confidence: 99%

“… Probiotics should not be considered as completely harmless, particularly in the immunodeficient host, and more safety studies are needed [100-110, 115,116].  Physiological use (normal route, normal dose, normal growth phase, specific strain or substrain/species) is studied in all cases, so as not to overwhelm (high dose) or circumvent natural immune processing [100][101][102][103][104][105][106][107][108][109][110].  Do probiotics really induce/exacerbate Th1 and / or Th2-mediated diseases?…”

mentioning

confidence: 99%

The Role of Probiotics in Atopic Dermatitis Prevention and Therapy

Özdemir¹

2012

Atopic Dermatitis - Disease Etiology and Clinical Management

View full text Add to dashboard Cite

Neonatal meningitis due to Lactobacillus

Cited by 46 publications

References 0 publications

Probiotics and Prebiotics in Pediatrics

Probiotics and Prebiotics in Pediatrics

Prophylactic Probiotics to Prevent Death and Nosocomial Infection in Preterm Infants

The Role of Probiotics in Atopic Dermatitis Prevention and Therapy

Contact Info

Product

Resources

About