Neonatal MRI in preterm infants with periventricular leukomalacia and mild disability

Abstract

Linear, spotted, or macular lesions that are hyperintense on T1-weighted imaging and hypointense on T2-weighted imaging are possibly compatible with periventricular leukomalacia.

Diffusion Tensor Imaging–Demonstrated Differences between Hemiplegic and Diplegic Cerebral Palsy with Symmetric Periventricular Leukomalacia

“…However, these evaluation tools are limited in that they do not allow the direct estimation or visualization of neural tracts; therefore, determination of the presence and extent of neural injury has been limited. [8][9][10][11][12][13] DTI is a recently introduced technique that allows the integrities of WM tracts to be estimated by virtue of its ability to visualize the diffusion characteristics of water. DTT is a 3D visualized version of DTI and thus provides concrete descriptions of the architecture and integrity of the CST.…”

Premature white matter disease

“…9) [22,48]. These lesions are usually detected within 3-4 d after birth and may be associated with mild surrounding T2 hyperintensity when large [22,48,49]. Pathologically, these signal changes are felt to reflect petechial hemorrhage or hypercellularity due to the destructive process [50,51].…”