Neonatal outcome in severe preeclampsia at 24 to 36 weeks' gestation: Does the HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome matter?

Abramovici, D.; Friedman, Steven A.; Mercer, Brian M.; Audibert, François; Kao, Lu; Sibai, Baha M.

doi:10.1016/s0002-9378(99)70178-x

Cited by 138 publications

(101 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Maternal age, gravidity, parity, gestational age at delivery, and mean arterial blood pressure were similar in both disorders. However, Haddad et al (8) showed that severe preeclampsia cases were younger than HELLP syndrome cases and another study found lower gestational age at delivery in HELLP syndrome cases (7).…”

Section: Discussionmentioning

confidence: 97%

See 1 more Smart Citation

Severe Preeclampsia versus HELLP Syndrome: Maternal and Perinatal Outcomes at <34 and ≥34 Weeks’ Gestation

Kinay¹,

Kucuk²,

Kayıkçıoğlu³

et al. 2015

Balkan Med J

View full text Add to dashboard Cite

Background: Preeclampsia and Hemolysis, Elevated Liver enzymes, Low Platelet (HELLP) syndrome are important disorders affecting the health of both the mother and fetus. Prediction of the maternal and perinatal outcomes at early and late gestational age is important for the management of both disorders. Aims: The purpose of the study was to investigate adverse maternal and perinatal outcomes in severe preeclampsia and HELLP syndrome cases according to gestational age. Study Design: Retrospective cross-sectional study. Methods: One hundred and ninety-seven pregnancies with severe preeclampsia and 56 pregnancies with HELLP syndrome were included the study. Clinical characteristics and adverse maternal and perinatal outcomes were noted from medical records. Participants were divided into two groups at <34 and ≥34 weeks' gestation: the severe preeclampsia group and the HELLP syndrome group. The differences between the outcomes in the groups were investigated. Statistical analysis was performed using the Student t test, Fisher Exact test and Yates' Chi-square test. Results: Eclampsia was more common in HELLP syndrome cases at <34 weeks' gestation (p 0.028). However, eclampsia rates were statistically similar between groups at ≥34 weeks' gestation. The requirement for blood products transfusion was higher in the HELLP group at all gestational weeks. No statistical difference was found in perinatal outcomes between severe preeclampsia and HELLP groups at less than and more than 34 weeks' gestation. Conclusion: Eclampsia risk increases in HELLP syndrome, especially at gestations less than 34 weeks. Perinatal morbidity at less than 34 weeks' gestation and mortality were similar in severe preeclampsia and HELLP syndrome cases at the same gestational age.

show abstract

Section: Discussionmentioning

confidence: 97%

“…Some studies have also shown that maternal morbidity risk is higher in HELLP syndrome cases than in severe preeclampsia (5)(6). In other studies, no significant difference was found for the maternal and perinatal outcomes between the two disorders (7)(8).…”

mentioning

confidence: 93%

Severe Preeclampsia versus HELLP Syndrome: Maternal and Perinatal Outcomes at <34 and ≥34 Weeks’ Gestation

Kinay¹,

Kucuk²,

Kayıkçıoğlu³

et al. 2015

Balkan Med J

View full text Add to dashboard Cite

show abstract

“…Earlier observations by Audibert et al suggest that there are fewer incidences of DIC and maternal and perinatal complications observed among women with partial HELLP over complete HELLP syndrome. 13 This emphasizes the fact of recognizing the condition distinctly from HELLP and the option of more conservative management. This is further supported by retrospective observations by Abbade et al, that there was a high rate of caesarean section rates and preterm delivery due to interruption of pregnancy with diagnosis of partial HELLP syndrome and such decisions needs review.…”

Section: Discussionmentioning

confidence: 99%

Thrombocytopenia in early pregnancy predicting partial haemolysis, elevated liver enzyme and low platelet count syndrome: a case report and review of literature

Nagandla

Kumar

Kovil³

2016

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

“…La mortalidad perinatal reportada en PES-HELLP es de 7,4 a 34% (31,32) y es mayor en los neonatos que nacen antes de las 32 semanas (33). En esta serie hubo 7 muertes en 23 casos (30,3%) confirmando el impacto de esta patología materna sobre el pronóstico perinatal.…”

Section: Sobrevivencia Perinatalunclassified

Morbilidad materna grave e ingreso a cuidado intensivo: Hospital Clínico Universidad de Chile (2006-2010)

Sepúlveda‐Martínez

et al. 2013

Rev. méd. Chile

View full text Add to dashboard Cite

show abstract

Neonatal outcome in severe preeclampsia at 24 to 36 weeks' gestation: Does the HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome matter?

Cited by 138 publications

References 13 publications

Severe Preeclampsia versus HELLP Syndrome: Maternal and Perinatal Outcomes at <34 and ≥34 Weeks’ Gestation

Severe Preeclampsia versus HELLP Syndrome: Maternal and Perinatal Outcomes at <34 and ≥34 Weeks’ Gestation

Thrombocytopenia in early pregnancy predicting partial haemolysis, elevated liver enzyme and low platelet count syndrome: a case report and review of literature

Morbilidad materna grave e ingreso a cuidado intensivo: Hospital Clínico Universidad de Chile (2006-2010)

Contact Info

Product

Resources

About