Neonatal outcome of extremely preterm Asian infants ⩽28 weeks over a decade in the new millennium

“…A number of recent cohort studies in the US 4,5 , France 7 , Japan 10 , Taiwan 11 , UK 12 , Sweden 13 , and Singapore 14 have provided estimates of GA-specific survival that can be utilized as a starting point for understanding outcomes and international variations in survival for EPT infants (Table 1). However, international comparisons of EPT survival among countries are limited by differences in the data sources, ascertainment of death, selection of denominators, and definitions of live-births 15 .…”

Section: Survivalmentioning

confidence: 99%

Short- and Long-Term Outcomes for Extremely Preterm Infants

2016

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Prematurity is the leading cause of infant mortality worldwide. In developed countries, extremely preterm infants contribute disproportionately to both neonatal and infant mortality. Survival of this high-risk population has incrementally improved in recent years. Despite these improvements, approximately 1 in 4 extremely preterm infants dies during the birth hospitalization. Among those who survive, respiratory and other morbidities are common, although their effect on quality of life is variable. In addition, long-term neurodevelopmental impairment is a large concern for patients, clinicians and families. However, the interplay of multiple factors contribute to neurodevelopmental impairment, with measures that change over time and outcomes that can be difficult to define and predict. Understanding outcomes of extremely preterm infants can help better counsel families regarding antenatal and postnatal care and guide strategies to improve survival without morbidity. This review summarizes recent evidence to provide an overview into the short- and long-term outcomes for extremely preterm infants.

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“…During the past 5 years, large cohort studies from developed nations in North America, 11–13,20,21 South America, 22 Europe, 14,15,23–25 Asia, 18,19,26 and Australia 27 have reported estimates of gestational age-specific survival following periviable birth. Direct comparisons of estimated survival rates among these studies are limited, however, by potential biases introduced from differences in the data sources, ascertainment of death, selection of denominators, and definitions of live birth.…”

Section: Estimates Of Gestational-age Specific Survivalmentioning

confidence: 99%

Survival of Infants Born at Periviable Gestational Ages

Patel

Rysavy

Bell

et al. 2017

Clinics in Perinatology

135

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Synopsis/abstract Periviable births are defined as births occurring from 20 0/7 through 25 6/7 weeks of gestation. Among and within developed nations, significant variation exists in the approach to obstetrical and neonatal care for periviable birth. Understanding gestational age-specific survival, including factors that may influence survival estimates and how these estimates have changed over time, may guide approaches to the care of periviable births and inform conversations with families and caregivers. This review provides a historical perspective on survival following periviable birth, summarizes recent and new data on gestational age-specific survival rates, and addresses factors that have a significant impact on survival.

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Neonatal outcome of extremely preterm Asian infants ⩽28 weeks over a decade in the new millennium

Abstract: Although there was no significant trend in neonatal survival or composite morbidity over the decade, improved survival and morbidity were seen with increasing GA.

Cited by 32 publications

References 46 publications

Prospective evaluation of the Ages and Stages Questionnaire 3rd Edition in very‐low‐birthweight infants

Prospective evaluation of the Ages and Stages Questionnaire 3rd Edition in very‐low‐birthweight infants

Short- and Long-Term Outcomes for Extremely Preterm Infants

Survival of Infants Born at Periviable Gestational Ages

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