2024
DOI: 10.1002/jsfa.13256
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Neonatal resveratrol administration promotes skeletal muscle growth and insulin sensitivity in intrauterine growth‐retarded suckling piglets associated with activation of FGF21–AMPKα pathway

Guangyi Bai,
Jinyong Chen,
Yue Liu
et al.

Abstract: BackgroundSkeletal muscle is the most major insulin‐sensitive tissue with a pivotal role in modulating glucose homeostasis. This study aimed to investigate the effect of resveratrol (RES) intervention during the suckling period on skeletal muscle growth and insulin sensitivity of neonates with intrauterine growth retardation (IUGR) in a pig model.Methods and resultsTwelve pairs of normal birth weight (NBW) and IUGR neonatal male piglets were selected. The NBW and IUGR piglets were fed basal formula milk diet o… Show more

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