Neonatal screening for congenital hypothyroidism in a developing country: problems and strategies

Pituitary Enlargement on Magnetic Resonance Imaging in Congenital Hypothyroidism

“…The worldwide incidence of congenital hypothyroidism is sig¬ nificant and is high (1:2481) in India. 23 Delayed diagno¬ sis and treatment, and inadequate therapy of congenital hypothyroidism is common in this country, with the con¬ dition being diagnosed after the age of 2 years in more than 50% of those affected. 24 The situation may be simi¬ lar in other developing countries.…”

Thyroid function determinants in cord blood of Nigerian neonates

“…The percentage at risk of developing congenital hypothyroidism in this study is large when compared to the worldwide incidence of 1 in 4000. 22 In two separate research in India using cord blood one TSH(µIU/ml) reported 1 in 248 23 and the other 1 in 600 neonates, 18 while in Iran 1 in 914 and 1 in 1700 was reported. 24,25 Correlation graph of T 4 against TSH as shown in figure 1 revealed a significant inverse relationship.…”

Newborn Screening for Congenital Hypothyroidism in India– Is OVERDUE

“…Newborn Screening for CHT is a well characterized disorder and systematic neonatal screening for congenital hypothyroidism was introduced in the early 1970 [5,6]. In India an estimated 10,000 babies are born with congenital hypothyroidism every year [7,8]. Recently, countries like Philippines and China too have commenced the screening because waiting for a symptomatic diagnosis of affected infants mean the baby will NEVER be normal [9][10][11][12][13].…”