Neonatal Type-2 Unilateral Herpes Simplex Blepharokeratoconjunctivitis after Cesarean Delivery

Abstract

Rarely, infection occurs in the uterus (5%) or in the postpartum period (10%) [2]. The clinical presentation of these infections has been divided into three groups, each of which is associated with different clinical manifestations and outcomes: (1) skin, eye, and mouth (SEM), when infections are confined to the skin, eyes, and mucosa (2) central nervous system (CNS), associated with lethargy, poor feeding, and seizures, in the absence or not of cutaneous lesions and (3) disseminated disease, involving multiple organs and

Congenital herpes simplex with ophthalmic and multisystem features: a case report

“…Herpes simplex eye disease can result in cataracts, corneal ulceration, anterior uveitis, vitritis, chorioretinitis, and optic atrophy and is the main cause of corneal visual loss in developed countries [ 9 , 15 ]. In the acute phase, conjunctivitis is the most frequent ophthalmologic symptom in neonates and is often associated with herpetic epithelial keratitis [ 16 ]. Corneal involvement, as in our case, is unilateral in approximately 90% of patients [ 15 ].…”

“…Considering that there is potential clinical overlap with other etiologies of conjunctival disease, such as gonococcal disease, diagnosis can be challenging [ 6 ]. Hence, it is essential to consider HSV infection in cases of neonatal conjunctivitis, especially in patients with an epithelial defect and no improvement after empiric treatment with topical antibiotics [ 16 ].…”