Neoplasms arising in large gastric hyperplastic polyps: endoscopic and pathologic features

Ahn, Ji Yong; Son, Da Hye; Choi, Kee Don; Roh, Jin; Lim, Hyun; Choi, Kyeong‐Hee; Lee, Jeong Hoon; Kim, Do Hoon; Song, Ho June; Lee, Gin Hyug; Jung, Hwoon Yong; Kim, Jin Ho; Han, Seungbong; Park, Young Su

doi:10.1016/j.gie.2014.04.020

Cited by 39 publications

(45 citation statements)

References 21 publications

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“…A female-to-male ratio of 3:1 was observed for the presence of gastric polyps in biopsies, and this difference was sustained from the year 2000 for the fundic gland and hyperplastic subtypes of polyps. Large (>1 cm) and pedunculated HPs have a higher risk of malignant transformation, although, in the present study, none of the polyps had epithelial dysplasia 13 . Moreover, adenomas were considered true premalignant conditions of the gastric mucosa, which can lead to carcinoma 14 .…”

Section: Discussioncontrasting

confidence: 76%

Changing Trends in Gastric Polyps

Velazquez-Dohorn¹,

López-Durand²,

Gamboa‐Domínguez³

2018

RIC

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Section: Discussioncontrasting

confidence: 76%

Changing Trends in Gastric Polyps

Velazquez-Dohorn¹,

López-Durand²,

Gamboa‐Domínguez³

2018

RIC

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“…드물게 과증식 위용종 으로 인한 위배출 장애 및 위장 폐쇄, 실혈 등의 증상이 나타날 수 있으며, 과증식 위용종의 0.6%에서 19%까지 위선암 및 위 이형성으로 변화한다는 보고가 있어 용종의 치료 방향을 설정 하는 것이 중요하다. [2][3][4][5][6][7] 과증식 위용종을 치료할 때에는 용종의 크기가 작고 증상이 없는 경우 대부분 주기적으로 추적 관찰을 하여 그 크기의 변화를 살펴볼 수 있으나, 용종의 크기가 1.0~2.0 cm 이상인 경우, 위용종으로 인한 위배출 장애나 실 혈 등의 중요 증상이 동반되는 경우 등에는 내시경적 절제를 하게 되며 필요하다면 수술적 제거도 고려한다. 8 헬리코박터 파일로리균(이하 헬리코박터)은 과증식 위용종의 원인이 되는 만성 위축성 위염의 대표적인 유발인자이며, 위선 암의 발생을 증가시키는 것으로 알려져 있다.…”

Section: 서 론unclassified

Change in Size of Gastric Hyperplastic Polyps after Helicobacter pylori Eradication: A Prospective Study

Yoo¹,

Park²,

Joo³

et al. 2019

Korean J Helicobacter Up Gastrointest Res

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Background/Aims: Helicobacter pylori (H. pylori) eradication is known to be effective for reducing the size of gastric hyperplastic polyps (HPPs). This study investigated the change in size of gastric HPPs after H. pylori eradication. Materials and Methods: This was a prospective study that enrolled 25 H. pylori-positive patients diagnosed as having HPPs at Korea University Guro Hospital between July 2015 and July 2016. If the patient wanted to receive eradication therapy, medication was given. If the patients refused eradication, only clinical follow-up was performed. All patients were subsequently followed up with endoscopic examination to determine any change in polyp size. Results: Eighteen of the 25 H. pylori-positive patients diagnosed as having HPPs were given an eradication regimen, and 17 were confirmed to have achieved successful eradication. Twelve (70.8%) of the 17 patients in the eradication group showed ≥50% reduction in size, while two (25.0%) of the eight patients in the non-eradication group showed 50% reduction. The polyp regression rate was significantly higher in the eradication group (P=0.03). A multivariate analysis revealed that H. pylori eradication (OR, 40.047; 95% CI, 1.112~1442.767; P=0.044) and female sex (OR, 12.947; 95% CI, 1.038~161.503; P=0.047) were significant predictive factors of HPP regression. Conclusions: H. pylori eradication is an effective therapeutic modality for gastric HPP regression.

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“…3,4 Hyperplastic polyp is the most common non-fundic gland polyp 9,13 and is associated with Helicobacter pylori infection, chronic gastritis, and pernicious anaemia. 9,10,13 It is most commonly found in the gastric antrum. 10 Most gastric hyperplastic polyps are benign, but 0.6% to 19% of them contain neoplasm (dysplasia or carcinoma).…”

Section: N T H E P a S T T H E D I A G N O S I S O F G A S T R O mentioning

confidence: 99%

“…[1][2][3][4][5][6][7][8] Gastric hyperplastic polyps are the most common type of non-fundic gland gastric polyps incidentally found during endoscopy. 9,10 They usually occur in the antrum and are rarely associated with dysplasia or carcinoma, with the reported risk being 0.6% to 19%. 2 Two cases of gastroduodenal intussusception caused by hyperplastic polyp have been reported, despite its high prevalence and its antral location.…”

mentioning

confidence: 99%