Nepetalactone Content and Antibacterial Activity of the Essential Oils from Different Parts of Nepeta persica

Abstract

The essential oils from the flower, leaf, stem and root of Nepeta persica Boiss., analyzed by GC and GC/MS, were shown to contain 4aβ,7α,7aβ-nepetalactone (58.5%, 62.3%, 66.2% and 27.1%, respectively), and 4aα,7α,7aβ-nepetalactone (33.0%, 28.3%, 24.9% and 7.6%, respectively). The other main component of the flower and stem oils was α-pinene (3.6% and 4.4%) and of the leaf oil β-ocimene (3.6%). In the root oil, other main constituents were α-pinene (40.4%), α-amorphene (5.3%), γcadinene (2.9%), and cis-calamenene (2.5%). Nepetalactone was the major component of the flower, leaf and stem oils, which are thus important sources of nepetalactone. Antibacterial activities of the flower, leaf, stem and root oils were evaluated using the micro-dilution broth method. Inhibitory effects on Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi and Enterococcus faecalis were recorded. The flower, leaf, stem, and root oils had difference activities against the test microorganisms. The antibacterial property of the essential oils might be ascribed to their high content of nepetalactone isomers.

Identification of volatile compounds produced by the bacteriumBurkholderia tropicathat inhibit the growth of fungal pathogens

“…Several of these volatile compounds, such as DMDS, methyl ketone and toluene, have been previously detected in the headspace of cultures of many strains of Pseudomonas spp and from B. cepacia cultured in trypticase soy 22 . Although diverse volatile compounds, for example, DMDS, are able to inhibit spore germination in other fungi, such as Paecilomyces lilacinus , Pochania chlamydospora and Chlonostachys rosea , 23 in this work we found novel compounds, including α-pinene, ocimene, limonene and fencona, which are typically associated with plants and fruits with antibacterial properties, 24 suggesting that they play an important role in the antagonistic antifungal mechanism associated with this bacterium.…”

A comparative study of effects of extraction solvents/techniques on percentage yield, polyhenolic composition, and antioxidant potential of various extracts obtained from stems ofNepeta leucophylla: RP-HPLC-DAD assessment of its polyhenolic constituents

“…The various species of genus Nepeta have been known to have a wide range of medicinal properties viz. anti‐spasmodic, anti‐tussive, diuretic, febrifuge, anti‐asthmatic, emmenagogue, diaphoretic, and sedative effects (Formisano, Rigano, & Senatore, ; Kumar, Mathela, Tewari, & Singh, ; Shafaghat and Oji, ). Further, many species of this genus have also been reported to use against the treatment of cardiac thrombosis, angina pectoris, liver, kidney, stomach, and tooth ailments (Formisano et al, ; Sharma and Cannoo, ).…”

Phyto-pharmacological aspects of Nepeta nuda L.: A systematic review

“…According to review, N. nuda possesses antimicrobial (Alim et al, 2009;Gormez et al, 2013;Smiljković et al, 2018;Ðordević et al, 2019) and virocidal activity (Angelova et al, 2016;Todorov et al, 2015), as well as antioxidant (Alim et al, 2009;Aras et al, 2016b;a;Cvetković et al, n.d.;Sarikurkcu et al, 2018;2019;Ðordević et al, 2019), anticancer (Kabalay et al, 2018), and allelopathic (Bozari et al, 2013;Bozok et al, 2017;Dragoeva et al, 2017) properties. It has been reported that nepetalactones have antibacterial, antifungal, insecticidal and antioxidant activities (Adiguzel et al, 2009;Grbic-Ljaljevic et al, 2008;Reichert et al, 2019;Shafaghat and Oji, 2010;Zhu et al, 2012). Apart from these activities, their enjoyable flavor and scent is an additional benefit.…”