Nephro-protective concept and drugs described in Unani system of medicine: A review

Abstract

Nephrotoxicity is a poisonous effect of some substances, both toxic chemicals and medication on the kidneys. A number of therapeutic agents like certain antibiotics, anticancer drugs and other synthetic molecules adversely affect the kidney resulting in life threatening renal diseases. Nephrotoxicity is one of the major problems in the current era. These drugs from the treasure of traditional systems of medicines can also be used to protect the renal function and delay the progression of renal damage that leads to several life threatening diseases. The Unani System of Medicine possesses a number of drugs which are effective in various renal disorders. Some of the single as well as compound formulations mentioned in Unani literature have been evaluated for their effects on renal disorders and reported to possess anti-inflammatory, diuretic, antioxidant and nephro-protective effects against known toxicants. The researchers are keen to develop some good and cost effective drugs from the sources of traditional medicine. In the present review paper, concept of nephro-protection and herbal drugs mentioned as nephro-protective in classical literature of Unani system of medicine will be elaborated.