2017
DOI: 10.1016/j.jaad.2017.02.003
|View full text |Cite
|
Sign up to set email alerts
|

Nephrogenic systemic fibrosis: A 15-year retrospective study at a single tertiary care center

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
5
0

Year Published

2018
2018
2023
2023

Publication Types

Select...
6
1

Relationship

0
7

Authors

Journals

citations
Cited by 11 publications
(5 citation statements)
references
References 10 publications
0
5
0
Order By: Relevance
“…It has been reported that free gadolinium ion causes muscle contraction, blood coagulation and impaired mitochondrial function (4). The macrocyclic and the ionic contrast agents have a strong bonding ability with the gadolinium ion, which are less toxic to the human body, and adverse reactions such as allergies and nephrogenic systemic fibrosis (NSF) (5)(6)(7). (II) According to pharmacokinetic characteristics; GBCAs based on principle distribution sites are divided into extracellular compartment and hepatobiliary contrast agents (8).…”
mentioning
confidence: 99%
“…It has been reported that free gadolinium ion causes muscle contraction, blood coagulation and impaired mitochondrial function (4). The macrocyclic and the ionic contrast agents have a strong bonding ability with the gadolinium ion, which are less toxic to the human body, and adverse reactions such as allergies and nephrogenic systemic fibrosis (NSF) (5)(6)(7). (II) According to pharmacokinetic characteristics; GBCAs based on principle distribution sites are divided into extracellular compartment and hepatobiliary contrast agents (8).…”
mentioning
confidence: 99%
“…Although the incidence of nephrogenic systemic fibrosis has dramatically declined in recent years, predominantly due to increased awareness of the risk of using gadolinium-based contrast agents in individuals with impaired renal function, patients with this condition could represent a suitable group in which to assess the efficacy of therapies to treat gadolinium excess. One case series reviewed the outcomes of eight patients with a clinical and histopathologic diagnosis of nephrogenic systemic fibrosis and the authors showed that there was a significant correlation (p ¼ 0.0286) between the improvement of renal function and the improvement of nephrogenic systemic fibrosis symptoms [81]. Of the four patients who had an improvement in their renal function, two were patients with end-stage renal failure who underwent successful kidney transplant and two had acute kidney injury that resolved; all of these four patients had improvements in their symptoms of nephrogenic systemic fibrosis [81].…”
Section: Clinical Studiesmentioning
confidence: 99%
“…One case series reviewed the outcomes of eight patients with a clinical and histopathologic diagnosis of nephrogenic systemic fibrosis and the authors showed that there was a significant correlation (p ¼ 0.0286) between the improvement of renal function and the improvement of nephrogenic systemic fibrosis symptoms [81]. Of the four patients who had an improvement in their renal function, two were patients with end-stage renal failure who underwent successful kidney transplant and two had acute kidney injury that resolved; all of these four patients had improvements in their symptoms of nephrogenic systemic fibrosis [81]. Of the remaining four patients, all had end-stage renal failure that progressed.…”
Section: Clinical Studiesmentioning
confidence: 99%
See 1 more Smart Citation
“…In the early 2000s, some patients developed a rare but debilitating disease called nephrogenic systemic fibrosis (NSF) [11,12]. Although this condition has largely been attributed to renal deficiencies in patients and is almost completely avoided today [13][14][15], these cases highlight the need for new contrast agents for patients with poor kidney function.…”
Section: Gadolinium-based Contrast Agentsmentioning
confidence: 99%